About our e-newsletters
- Free e-newsletters
- Mayo Clinic expertise
- We do not share your e-mail address
Housecall, our weekly general-interest e-newsletter, keeps you up to date on a wide variety of health topics with timely, reliable, practical information, recipes, blogs, questions and answers with Mayo Clinic experts and more. Our biweekly topic-specific e-newsletters also include blogs, questions and answers with Mayo Clinic experts, and other useful information that will help you manage your health.
Housecall Archives
Mayo Clinic Housecall
Stay up to date on the latest health information.
What you get
- Free weekly e-newsletter
- Mayo Clinic expertise
- Recipes, tools and other helpful information
- We do not share your e-mail address
Causes
By Mayo Clinic staffDoctors don't know exactly what causes most cases of dystonia, but a few factors may be involved.
Altered nerve cell communication
Dystonia has been linked to altered communication between nerve cells located in the basal ganglia — an area of the brain involved in initiating muscle contractions.
Genetic changes
Researchers have also discovered a number of genetic changes associated with certain inherited forms of dystonia and also with other forms of dystonia. However, most cases of adult-onset focal dystonias have not been linked to genes.
Other disorders
Sometimes dystonia is but one symptom of a more pervasive disorder that affects the basal ganglia, such as:
- Parkinson's disease
- Huntington's disease
- Traumatic brain injury
- Stroke
- Brain tumor
- Oxygen deprivation
- Infections, such as tuberculosis or encephalitis
- Reactions to certain drugs
- Heavy metal or carbon monoxide poisoning
- Dystonias fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/dystonias/detail_dystonias.htm. Accessed Jan. 21, 2010.
- Tarsy D, et al. Dystonia. New England Journal of Medicine. 2006;355:818.
- Comella C. Treatment of dystonia. http://www.uptodate.com/home/index.html. Accessed Jan. 18, 2010.
- Schwarz CS, et al. Genetics and treatment of dystonia. Neurologic Clinics. 2009;27:697.
- Dystonias. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec16/ch221/ch221c.html. Accessed Jan. 21, 2010.
- Ropper AH, et al. Abnormalities of movement and posture caused by disease of the basal ganglia. In: Ropper AH, et al. Adams and Victor's Principles of Neurology. 9th ed. New York, N.Y.: McGraw-Hill Medical; 2009. http://www.accessmedicine.com/content.aspx?aID=3630437. Accessed Jan. 21, 2010.
- Complementary therapy. Dystonia Medical Research Foundation. http://www.dystonia-foundation.org/pages/complementary_therapy/156.php. Accessed Jan. 22, 2010.
- Ahlskog EJ (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 27, 2010.
Find Mayo Clinic on