Ebola virus and Marburg virus

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Complications

By Mayo Clinic staff

Both Ebola and Marburg hemorrhagic fevers lead to death for a high percentage of people who are affected. As the illness progresses, it can cause:

  • Multiple organ failure
  • Severe bleeding
  • Jaundice
  • Delirium
  • Seizures
  • Coma
  • Shock

One reason the viruses are so deadly is that they interfere with the immune system's ability to mount a defense. But scientists don't understand why some people recover from Ebola and Marburg and others don't.

For people who survive, recovery is slow. It may take months to regain weight and strength, and the viruses remain in the body for many weeks. People may experience:

  • Hair loss
  • Sensory changes
  • Liver inflammation (hepatitis)
  • Weakness
  • Fatigue
  • Headaches
  • Eye inflammation
  • Testicular inflammation
References
  1. Ebola hemorrhagic fever fact sheet. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/Fact_Sheets/Ebola_Fact_Booklet.pdf. Accessed April 25, 2011.
  2. Marburg hemorrhagic fever fact sheet. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/fact_sheets/fact_sheet_marburg_hemorrhagic_fever.pdf. Accessed April 25, 2011.
  3. Bray M. Epidemiology, pathogenesis and clinical manifestations of Ebola and Marburg hemorrhagic fever. http://www.uptodate.com/home/index.html. Accessed April 25, 2011.
  4. Peters CJ. Marburg and Ebola virus hemorrhagic fevers. In: Mandell JE, et al. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2010. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-443-06839-3..X0001-X--TOP&isbn=978-0-443-06839-3&uniqId=230100505-57. Accessed April 25, 2011.
  5. Bray M. Diagnosis and treatment of Ebola and Marburg hemorrhagic fever. http://www.uptodate.com/home/index.html. Accessed April 25, 2011.
DS00996 June 18, 2011

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