Ebola virus and Marburg virus

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Symptoms

By Mayo Clinic staff

Signs and symptoms of hemorrhagic fevers caused by Ebola virus and Marburg virus start abruptly within a few days to a week or more after infection. Early signs and symptoms include:

  • Fever
  • Severe headache
  • Joint and muscle aches
  • Chills
  • Sore throat
  • Weakness

Over time, symptoms become increasingly severe and may include:

  • Nausea and vomiting
  • Diarrhea (may be bloody)
  • Red eyes
  • Raised rash
  • Chest pain and cough
  • Stomach pain
  • Severe weight loss
  • Confusion, irritability or aggression
  • Massive hemorrhaging from many sites, including nose, mouth, rectum, eyes and ears
References
  1. Ebola hemorrhagic fever fact sheet. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/Fact_Sheets/Ebola_Fact_Booklet.pdf. Accessed March 29, 2009.
  2. Questions and answers about Ebola hemorrhagic fever. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvrd/Spb/mnpages/dispages/ebola/qa.htm. Accessed March 29, 2009.
  3. Questions and answers about Marburg hemorrhagic fever. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/marburg/qa.htm. Accessed March 29, 2009.
  4. Centers for Disease Control and Prevention. Notice to readers update: Management of patients with suspected viral hemorrhagic fever - United States. MMWR. 1995;44:475. http://www.cdc.gov/mmwr/preview/mmwrhtml/00038033.htm. Accessed March 29, 2009.
  5. Ebola hemorrhagic fever. World Health Organization. http://www.who.int/csr/disease/ebola/en. Accessed March 29, 2009.
  6. Marburg hemorrhagic fever. World Health Organization. http://www.who.int/csr/disease/marburg/en. Accessed March 29, 2009.
  7. Marburg hemorrhagic fever, imported case - United States. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvrd/spb/outbreaks/index.htm. March 29, 2009.
  8. Ebola/Marburg vaccine development. National Institute of Allergy and Infectious Diseases. http://www3.niaid.nih.gov/topics/ebolaMarburg. Accessed April 9, 2009.
  9. Peters CJ. Marburg and Ebola - Arming ourselves against the deadly filoviruses. New England Journal of Medicine. 2005;352:2571.
  10. Towner JS, et al. Marburg virus infection detected in a common African bat. PLoS (Public Library of Science) One. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.000076Accessed April 11, 2009.

DS00996

June 20, 2009

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