Ehrlichiosis

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Causes

By Mayo Clinic staff

Ehrlichiosis is caused by Ehrlichia chaffeensis bacteria and is transmitted primarily by the Lone Star tick.

Ticks feed on blood, latching onto a host and feeding until they're swollen to many times their normal size. During feeding, ticks that carry disease-producing bacteria can transmit the bacteria to a healthy host. Or they may pick up bacteria themselves if the host, such as a white-tailed deer or a coyote, is infected.

Usually, to get ehrlichiosis, you must be bitten by an infected tick. The bacteria enter your skin through the bite and eventually make their way into your bloodstream. Before bacteria can be transmitted, a tick must be attached and feeding for at least 24 hours. An attached tick with a swollen appearance may indicate that the tick has been feeding long enough to have transmitted bacteria. Removing ticks as soon as possible may prevent infection.

It's also possible that ehrlichiosis may be transmitted through blood transfusions, from mother to fetus and through direct contact with an infected, slaughtered animal.

References
  1. Sexton DJ. Human ehrlichiosis and anaplasmosis. http://www.uptodate.com/home/index.html. Accessed Jan. 29, 2010.
  2. Prevention and control. Centers for Disease Control and Prevention. http://www.cdc.gov/ticks/prevention.html. Accessed Feb. 24, 2010.
  3. Questions and answers. Centers for Disease Control and Prevention. http://www.cdc.gov/ticks/diseases/ehrlichiosis/faq.html. Accessed Feb. 24, 2010.
  4. Stone JH, et al. Human monocytic ehrlichiosis. Journal of the American Medical Association. 2004;292:2263.
  5. Ganguly S, et al. Tick-borne ehrlichiosis infection in human beings. Journal of Vector Borne Disease. 2008;45:273.
  6. Walker DH, et al. Rickettsial diseases. In: Fauci AS, et al. Harrison's Principles of Internal Medicine. 17th ed. New York, N.Y.: McGraw-Hill Medical; 2008. http://www.accessmedicine.com/content.aspx?aID=2898577. Accessed Feb. 25, 2010.
  7. Elston DM. Tick bites and skin rashes. Current Opinion in Infectious Diseases. In press. Accessed Feb. 24, 2010.
  8. Other tick-borne diseases. American Lyme Disease Foundation. http://www.aldf.com/Ehrlichiosis.shtml. Accessed Feb. 25, 2010.
  9. Removing ticks. Centers for Disease Control and Prevention. http://www.cdc.gov/ticks/tick_removal.html. Accessed Feb. 25, 2010.
  10. Prevention of tickborne infections. American Academy of Pediatrics. http://aapredbook.aappublications.org/cgi/content/full/2009/1/2.13?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=prevention+of+tickborne&searchid=1&FIRSTINDEX=0&volume=2009&issue=1&resourcetype=HWCIT. Accessed Feb. 26, 2010.
DS00702 April 17, 2010

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