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Risk factors

By Mayo Clinic staff

Factors that increase your risk of developing emphysema include:

  • Smoking. Emphysema is most likely to develop in cigarette smokers, but cigar and pipe smokers also are susceptible. The risk for all types of smokers increases with the number of years and amount of tobacco smoked.
  • Age. Although the lung damage that occurs in emphysema develops gradually, most people with tobacco-related emphysema begin to experience symptoms of the disease between the ages of 40 and 60.
  • Exposure to secondhand smoke. Secondhand smoke, also known as passive or environmental tobacco smoke, is smoke that you inadvertently inhale from someone else's cigarette, pipe or cigar. Being around secondhand smoke increases your risk of emphysema.
  • Occupational exposure to fumes or dust. If you breathe fumes from certain chemicals or dust from grain, cotton, wood or mining products, you're more likely to develop emphysema. This risk is even greater if you smoke.
  • Exposure to indoor and outdoor pollution. Breathing indoor pollutants, such as fumes from heating fuel, as well as outdoor pollutants — car exhaust, for instance — increases your risk of emphysema.
References
  1. Shapiro SD, et al. Chronic bronchitis and emphysema. In: Mason RJ, et al. Murray and Nadel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/das/book/body/192068760-2/0/1288/0.html. Accessed Feb. 24, 2011.
  2. What is COPD? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/Copd/Copd_WhatIs.html. Accessed Feb. 24, 2011.
  3. Anthonisen N. Chronic obstructive pulmonary disease. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Feb. 24, 2011.
  4. Chronic obstructive pulmonary disease. In: Ferri FF. Ferri's Clinical Advisor 2011: Instant Diagnosis and Treatment. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-05610-6..C2009-0-38600-6--TOP&isbn=978-0-323-05610-6&about=true&uniqId=230100505-53. Accessed Feb. 24, 2011.
  5. Rennard SI. Chronic obstructive pulmonary disease: Definition, clinical manifestations, diagnosis and staging. http://www.uptodate.com/home/index.html. Accessed Feb. 24, 2011.
  6. Rennard SI. Management of chronic obstructive pulmonary disease. http://www.uptodate.com/home/index.html. Accessed Feb. 25, 2011.
  7. Pulmonary rehabilitation: A team approach to improving quality of life. American College of Chest Physicians. http://www.chestnet.org/accp/patient-guides/pulmonary-rehabilitation-team-approach-improving-quality-life. Accessed Feb. 25, 2011.
  8. What is oxygen therapy? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/oxt/oxt_all.html. Accessed Feb. 25, 2011.
DS00296 April 29, 2011

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