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Treatments and drugs
By Mayo Clinic staffTreatment for mild cases mainly consists of:
- Rest
- A healthy diet, including plenty of liquids
- Using acetaminophen (Tylenol, others) to relieve headaches and fever
More serious cases of encephalitis can be difficult to treat because the viruses that cause the disease generally don't respond to medications. However, some viruses, particularly the herpes simplex virus and varicella-zoster virus, respond to antiviral drugs such as acyclovir (Zovirax). If you have one of these kinds of virus-induced encephalitis, your doctor will likely start treatment with acyclovir immediately. Another antiviral that's sometimes used is ganciclovir (Cytovene).
In addition to antiviral medications, your doctor may also treat you with:
- Anti-inflammatory drugs, such as corticosteroids, to help reduce swelling and pressure within your skull
- Anticonvulsant medications to stop or prevent seizures
After the illness, you may also need physical and speech therapy.
- Encephalitis and meningitis fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/encephalitis_meningitis/detail_encephalitis_meningitis.htm. Accessed March 21, 2009.
- Tyler KL. West Nile virus infection in the United States. Archives of Neurology. 2004;61:1190.
- Johnson RP. Viral encephalitis in adults. http://www.uptodate.com/home/index.html. Accessed March 12, 2009.
- Willoughbly RE Jr, et al. Encephalitis, meningoencephalitis, acute disseminated encephalomyelitis, and acute necrotizing encephalopathy. In: Long SS, et al. Principles and Practice of Pediatric Infectious Diseases. 3rd ed. Philadelphia, Pa.: Churchill Livingstone; 2008. http://www.mdconsult.com/das/book/body/127224884-3/819357724/1679/50.html#4-u1.0-B978-0-443-06687-0..50049-7--cesec19_1078. Accessed March 21, 2009.
- Eastern equine encephalitis fact sheet. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvbid/arbor/eeefact.htm. Accessed March 21, 2009.
- St. Louis encephalitis fact sheet. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvbid/sle/Sle_FactSheet.html. Accessed March 21, 2009.
- LaCrosse encephalitis. Directors of Health Promotion and Education. http://www.dhpe.org/lacenceph.asp. Accessed March 21, 2009.
- Peters CJ. Infections caused by arthropod- and rodent-borne viruses. In: Fauci AS, et al. Harrison's Principles of Internal Medicine. 17th ed. New York, N.Y.: McGraw-Hill Medical; 2008. http://www.accessmedicine.com/content.aspx?aID=2895916. Accessed March 21, 2009.
- Encephalitis. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec16/ch217/ch217c.html. Accessed March 21, 2009.
- Voelker R. Effects of West Nile virus may persist. Journal of the American Medical Association. 2008;299:2135.
- Insect repellant use and safety. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvbid/westnile/qa/insect_repellent.htm. Accessed March 22, 2009.
- Follow safety precautions when using DEET on children. American Academy of Pediatrics. http://www.aap.org/family/wnv-jun03.htm. Accessed March 22, 2009.
