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Definition

By Mayo Clinic staff

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Illustration showing effects of endocarditis on the heart
Endocarditis

Endocarditis is an infection of the inner lining of your heart (endocardium).

Endocarditis typically occurs when bacteria or other germs from another part of your body, such as your mouth, spread through your bloodstream and attach to damaged areas in your heart. Left untreated, endocarditis can damage or destroy your heart valves and can lead to life-threatening complications. Treatments for endocarditis include antibiotics and, in severe cases, surgery.

Endocarditis is uncommon in people with healthy hearts. People at greatest risk of endocarditis have a damaged heart valve, an artificial heart valve or other heart defects.

References
  1. Infective endocarditis. American Heart Association. http://www.heart.org/HEARTORG/Conditions/CongenitalHeartDefects/TheImpactofCongenitalHeartDefects/Infective-Endocarditis_UCM_307108_Article.jsp. Accessed June 6, 2011.
  2. Endocarditis. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/endo/endo_all.html. Accessed June 19, 2009.
  3. Sexton DJ. Diagnostic approach to infective endocarditis. http://www.uptodate.com/home/index.html. Accessed June 2, 2011.
  4. Sexton DJ. Epidemiology, risk factors and microbiology of infective endocarditis. http://www.uptodate.com/home/index.html. Accessed June 2, 2011.
  5. Spelman D, et al. Complications and outcome of infective endocarditis. http://www.uptodate.com/home/index.html. Accessed June 2, 2011.
  6. Sexton DJ. Antimicrobial therapy of native valve endocarditis. http://www.uptodate.com/home/index.html. Accessed June 2, 2011.
  7. Schick EC. Surgery for native valve endocarditis. http://www.uptodate.com/home/index.html. Accessed June 2, 2011.
  8. Delahaye F. Is early surgery beneficial in infective endocarditis? A systematic review. Archives of Cardiovascular Disease. 2011:104:35.
  9. Burton MJ, et al. Infective endocarditis prevention: Update on 2007 guidelines. The American Journal of Medicine. 2007;11:484.
DS00409 Aug. 11, 2011

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