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Symptoms

By Mayo Clinic staff

Endocarditis may develop slowly or suddenly — depending on what's causing the infection and whether you have any underlying heart problems. The infection can infect different people differently, so signs and symptoms vary. They may include:

  • Fever
  • Chills
  • A new or changed heart murmur — abnormal heart sounds made by blood rushing through your heart
  • Fatigue
  • Aching joints and muscles
  • Night sweats
  • Shortness of breath
  • Paleness
  • Persistent cough
  • Swelling in your feet, legs or abdomen
  • Unexplained weight loss
  • Blood in your urine (either visible or found in a doctor's viewing of your urine under a microscope)
  • Tenderness in your spleen — an infection-fighting abdominal organ on your left side, just below your rib cage
  • Osler's nodes — red, tender spots under the skin of your fingers
  • Petechiae (puh-TEE-key-e) — tiny purple or red spots on the skin, whites of your eyes or inside your mouth

When to see a doctor
If you develop signs or symptoms of endocarditis, see your doctor right away — especially if you have risk factors for this serious infection, such as a heart defect or a previous case of endocarditis.

Although less serious conditions can cause similar signs and symptoms, you won't know for sure until you're evaluated.

References
  1. Infective endocarditis. American Heart Association. http://www.heart.org/HEARTORG/Conditions/CongenitalHeartDefects/TheImpactofCongenitalHeartDefects/Infective-Endocarditis_UCM_307108_Article.jsp. Accessed June 6, 2011.
  2. Endocarditis. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/endo/endo_all.html. Accessed June 19, 2009.
  3. Sexton DJ. Diagnostic approach to infective endocarditis. http://www.uptodate.com/home/index.html. Accessed June 2, 2011.
  4. Sexton DJ. Epidemiology, risk factors and microbiology of infective endocarditis. http://www.uptodate.com/home/index.html. Accessed June 2, 2011.
  5. Spelman D, et al. Complications and outcome of infective endocarditis. http://www.uptodate.com/home/index.html. Accessed June 2, 2011.
  6. Sexton DJ. Antimicrobial therapy of native valve endocarditis. http://www.uptodate.com/home/index.html. Accessed June 2, 2011.
  7. Schick EC. Surgery for native valve endocarditis. http://www.uptodate.com/home/index.html. Accessed June 2, 2011.
  8. Delahaye F. Is early surgery beneficial in infective endocarditis? A systematic review. Archives of Cardiovascular Disease. 2011:104:35.
  9. Burton MJ, et al. Infective endocarditis prevention: Update on 2007 guidelines. The American Journal of Medicine. 2007;11:484.
DS00409 Aug. 11, 2011

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