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Risk factors

By Mayo Clinic staff

You may be more likely to experience enlarged liver if you have a liver disease. Factors that may increase your risk of liver problems include:

  • Excessive alcohol use. Drinking large amounts of alcohol can be damaging to your liver.
  • Large doses of over-the-counter medicines. Taking larger than recommended doses of certain over-the-counter medicines, such as acetaminophen (Tylenol, others), can increase your risk of liver damage.
  • Certain herbal supplements. Certain supplements can increase your risk of liver damage, including black cohosh and mistletoe.
  • Certain infections. Infectious diseases that can increase your risk of liver damage include malaria and Q fever.
  • Hepatitis viruses. Hepatitis A, B and C can cause liver damage.
References
  1. Bergasa NV. Approach to the patient with liver disease. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/178983847-2/0/1492/0.html. Accessed Jan. 19, 2010.
  2. Hepatomegaly. In: Ferri FF. Ferri's Clinical Advisor 2010. Philadelphia, Pa.: Mosby; 2010. http://www.mdconsult.com/das/book/body/1785151917/0/2088/0.html. Accessed Jan. 15, 2010.
  3. Seeff LB. Herbal hepatoxicity. Clinics in Living Disease. 2007;11:577.
  4. Liver wellness. American Liver Foundation. http://www.liverfoundation.org/downloads/alf_download_29.pdf. Accessed Jan. 19, 2010.
  5. Wolf AD, et al. Hepatomegaly in neonates and children. Pediatrics in Review. 2000;21:303.
DS00638 Feb. 27, 2010

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