Free
E-newsletter
Subscribe to Housecall
Our weekly general interest
e-newsletter keeps you up to date
on a wide variety of health topics.
Mayo Clinic Housecall
Stay up to date on the latest health information.
What you get
- Free weekly e-newsletter
- Mayo Clinic expertise
- Recipes, tools and other helpful information
- We do not share your e-mail address
Treatments and drugs
By Mayo Clinic staffEpididymitis caused by a sexually transmitted infection (STI) or other infection is treated with antibiotic medications. Your sexual partner will also need treatment. Make sure your doctor is aware of any other medications you're taking or any allergies you have. This information, as well as determining what type of infection you have, will help your doctor select the best treatment.
Be sure to take the entire course of antibiotics prescribed by your doctor, even though you may feel better in one to three days after you start treatment. If you're not feeling better in that time, contact your doctor.
When you've finished your medication, it's a good idea to return to your doctor for a follow-up visit to be sure that the infection has cleared up. If it hasn't, your doctor may try another antibiotic. If the infection still doesn't clear, your doctor may do further tests to determine whether your epididymitis is caused by something other than a bacterial infection or an STI.
If a pocket of pus (abscess) has formed, it may need to be drained, and in some cases part or all of the epididymis needs to be removed surgically (epididymectomy). Surgery may also be considered if epididymitis is due to underlying physical defects, but many people continue to have scrotal pain following epididymectomy.
- Nickel JC. Inflammatory conditions of the male genitourinary tract: Prostatitis and related conditions, orchitis, and epididymitis. In: Wein AJ, et al. Campbell-Walsh Urology. 10th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/208746819-6/0/1445/0.html. Accessed Aug. 15, 2011.
- Fort GG. Epididymitis. In: Ferri FF. Ferri's Clinical Advisor 2011: Instant Diagnosis and Treatment. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-05610-6..C2009-0-38600-6--TOP&isbn=978-0-323-05610-6&about=true&uniqId=230100505-53. Accessed Aug. 15, 2011.
- Yin S, et al. Diagnosis and management of testicular torsion, torsion of the appendix testis, and epididymitis. Clinical Pediatric Emergency Medicine. 2009;10:38.
- Trojian T, et al. Epididymitis and orchitis: An overview. American Family Physician. 2009;79:583.
- Schneck FX, et al. Abnormalities of the testes and scrotum and their surgical management. In: Wein AJ, et al. Campbell-Walsh Urology. 10th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/208746819-6/0/1445/0.html. Accessed Aug. 15, 2011.
- Nippoldt TB (expert opinion). Mayo Clinic, Rochester, Minn. Aug. 29, 2011.
Find Mayo Clinic on