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Definition

By Mayo Clinic staff

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Illustration of the anatomy of the throat 
Throat anatomy

Epiglottitis is a potentially life-threatening condition that occurs when the epiglottis — a small cartilage "lid" that covers your windpipe — swells, blocking the flow of air into your lungs.

A number of factors can cause the epiglottis to swell — burns from hot liquids, direct injury to your throat and various infections. The most common cause of epiglottitis in children in the past was infection with Haemophilus influenzae type b (Hib), the same bacterium that causes pneumonia, meningitis and infections in the bloodstream. Epiglottitis can occur at any age.

Routine Hib vaccination for infants has made epiglottitis rare, but epiglottitis remains a concern. If you suspect that you or someone in your family has epiglottitis, seek emergency help immediately. Prompt treatment can prevent life-threatening complications.

References
  1. Epiglottitis. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec08/ch090/ch090l.html. Accessed May 17, 2012.
  2. Is your child protected against Hib? Centers for Disease Control and Prevention. http://www.cdc.gov/Features/HibDisease/. Accessed May 17, 2012.
  3. Haemophilus influenzae type b (Hib) vaccine. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/pubs/vis/downloads/vis-hib.pdf. Accessed May 19, 2012.
  4. Hay WW, et al. Current Diagnosis & Treatment: Pediatrics. 20th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/content.aspx?aID=6582059. Accessed May 17, 2012.
  5. Grover C. Thumb sign of epiglottitis. The New England Journal of Medicine. 2011;365:447.
  6. Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/content.aspx?aID=9097038. Accessed May 17, 2012.
  7. Lalwani AK. Current Diagnosis & Treatment in Otolaryngology - Head & Neck Surgery. 3rd ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/content.aspx?aID=55768949. Accessed May 17, 2012.
  8. Kavanagh KR, et al. Traumatic epiglottitis after foreign body ingestion. Journal of Pediatric Otorhinolaryngology. 2008;72:901.
  9. Shah RK, et al. Epiglottitis in the United States: National trends, variances, prognosis and management. Laryngoscope. 2010;120:1256.
  10. Valdez-Lowe C, et al. Pulse oximetry in adults. American Journal of Nursing. 2009;109:52.
DS00529 Oct. 2, 2012

© 1998-2013 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

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