Epiglottitis

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Causes

By Mayo Clinic staff

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Illustration of the throat Your throat

Your voice box (larynx) is a framework of cartilage, muscle and mucous membrane that forms the entrance to your windpipe (trachea), the tube that connects your mouth and throat to your lungs. The epiglottis is a small, movable "lid" just above the larynx that prevents food and drink from entering your windpipe.

It does this by dropping down when you swallow, effectively sealing off the larynx. That's why you can't swallow and breathe at the same time. When you're not eating or drinking, the epiglottis is slightly lifted so that air can flow freely into your lungs. But if the epiglottis becomes swollen — either from infection or from injury — the airway narrows and may become completely blocked.

Infection
The most common cause of swelling and inflammation of the epiglottis and surrounding tissues is infection with Haemophilus influenzae type b (Hib) bacteria. Hib isn't the germ that causes the flu, but it's responsible for other serious conditions — including respiratory tract infections and meningitis.

Hib spreads through infected droplets coughed or sneezed into the air. It's possible to harbor Hib in your nose and throat without becoming sick — though you still have the potential to spread the bacteria to others.

Other bacteria and viruses also can cause inflammation of the epiglottis, including:

  • Streptococcus pneumoniae (pneumococcus), another bacterium that causes meningitis, pneumonia, ear infections and blood infection (sepsis)
  • Streptococcus A, B and C, a group of bacteria that cause diseases ranging from strep throat to blood infections
  • Candida albicans, the fungus responsible for vaginal yeast infections, diaper rash and oral thrush
  • Varicella zoster, the virus responsible for chickenpox and shingles

Injury
Physical injury, such as a direct blow to the throat, can cause epiglottitis. So can scald burns to your face or burns from drinking very hot liquids.

You also may develop signs and symptoms similar to those of epiglottitis if you:

  • Swallow a chemical that burns your throat
  • Swallow a foreign object
  • Smoke drugs such as crack cocaine and heroin

DS00529

May 3, 2008

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