Esophageal varices

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Risk factors

By Mayo Clinic staff

Although many people with advanced liver disease develop esophageal varices, most won't experience bleeding. Varices are more likely to bleed if you have:

  • High portal vein pressure. The risk of bleeding increases with the amount of pressure in the portal vein.
  • Large varices. The larger the varices, the more likely they are to bleed.
  • Red marks on the varices. When viewed through an endoscope — a lighted tube that's passed down your throat — some varices show long, red streaks or red spots. These marks indicate a high risk of bleeding.
  • Severe cirrhosis or liver failure. Most often, the more severe your liver disease, the more likely varices are to bleed.
  • Continued alcohol use. If your liver disease is alcohol related, your risk of variceal bleeding is far greater if you continue to drink than if you stop.
References
  1. Shah VH, et al. Portal hypertension and gastrointestinal bleeding. In: Feldman M, et al. Sleisinger and Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, Pa.: Saunders; 2010. http://www.mdconsult.com/book/player/linkTo?type=bookHome&isbn=978-1-4160-6189-2&eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&uniq=200844987-3. Accessed Sept. 12, 2010.
  2. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis. Alexandria, Va.: American Association for the Study of Liver Diseases. http://www.aasld.org/practiceguidelines/Documents/Bookmarked%20Practice%20Guidelines/Prevention%20and%20Management%20of%20Gastro%20Varices%20and%20Hemorrhage.pdf. Accessed Sept. 12, 2010.
  3. Cirrhosis. National Institute for Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/cirrhosis/index.htm. Accessed Sept. 12, 2010.
  4. Schistosomiasis. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dpd/parasites/schistosomiasis/factsht_schistosomiasis.htm. Accessed Sept. 12, 2010.
DS00820 Oct. 30, 2010

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