Definition
By Mayo Clinic staffMelanoma is a type of cancer that develops in the cells that produce melanin — the pigment that gives your skin its color. Your eyes also have melanin-producing cells and can develop melanoma. Eye melanoma is also called ocular melanoma.
Most eye melanomas form in the part of the eye you can't see when looking in a mirror. This makes eye melanoma difficult to detect. In addition, eye melanoma typically doesn't cause early signs or symptoms.
Treatment is available for eye melanomas. Treatments for some small eye melanomas may not interfere with your vision. However, treatment for large eye melanomas typically causes some vision loss.
- Augsburger JJ, et al. Uveal melanoma. In: Yanoff M, et al. Ophthalmology. 3rd ed. Philadelphia, Pa.: Mosby; 2008. http://www.mdconsult.com/das/book/body/199400089-5/0/1869/0.html. Accessed May 4, 2010.
- Intraocular (eye) melanoma treatment. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/intraocularmelanoma/patient/allpages. Accessed May 4, 2010.
- Simar K. The fundamentals of uveal melanoma. Clinical Journal of Oncology Nursing. 2009;13:483.
- Shields CL, et al. Ocular melanoma: Relatively rare but requiring respect. Clinics in Dermatology. 2009;27:122.
- Gragoudas ES, et al. Ocular melanoma. http://www.uptodate.com/home/index.html. Accessed May 6, 2010.
- Surgical procedures. American Society of Ocularists. http://www.ocularist.org/resources_surgical_procedures.asp. Accessed May 6, 2010.
- Ihrig C, et al. Acquired monocular vision rehabilitation program. Journal of Rehabilitation Research & Development. 2007;44:593.
- Occupational therapy services for individuals with visual impairment. American Occupational Therapy Association. http://www.aota.org/Practitioners/PracticeAreas/Rehab/Tools/38508.aspx. Accessed May 6, 2010.
- Shopping guide for sunglasses. American Optometric Association. http://www.aoa.org/documents/SunglassShoppingGuide0810.pdf. Accessed May 6, 2010.
- Roberston DM (expert opinion). Mayo Clinic, Rochester, Minn. May 22, 2010.
- How is eye cancer diagnosed? American Cancer Society. http://www.cancer.org/docroot/cri/content/cri_2_4_3x_how_is_eye_cancer_diagnosed_74.asp. Accessed May 24, 2010.
- Surgery. American Cancer Society. http://www.cancer.org/docroot/CRI/content/CRI_2_4_4X_Surgery_74.asp?rnav=cri. Accessed May 24, 2010.
- Damato B, et al. Surgical resection of uveal melanoma. In: Albert DM, et al. Albert & Jakobiec's Principles and Practice of Ophthalmology. 3rd ed. Philadelphia, Pa.: Saunders Elsevier;2008:4913.

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