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Alternative medicine

By Mayo Clinic staff

Evening primrose oil is a form of linoleic acid that's available as an over-the-counter supplement. Many women use evening primrose oil — taking one capsule up to three times a day — to manage breast pain and other symptoms of fibrocystic breast changes. Although the exact mechanism is unknown, experts speculate that evening primrose oil may replace linoleic acid in women who are deficient in this essential fatty acid. Restoring linoleic acid levels may make their breast tissues less sensitive to hormonal influences.

References
  1. Non-cancerous breast conditions. American Cancer Society. http://www.cancer.org/docroot/CRI/content/CRI_2_6X_Non_Cancerous_Breast_Conditions_59.asp. Accessed June 16, 2010.
  2. Giuliano AE, et al. Breast disorders. In: McPhee SJ, et al. Current Medical Diagnosis & Treatment 2010. New York, N.Y.: McGraw-Hill Medical; 2010. http://www.accessmedicine.com/content.aspx?aID=8538. Accessed June 16, 2010.
  3. Valea FA, et al. Breast diseases: Diagnosis and treatment of benign and malignant disease. In: Katz VL, et al. Comprehensive Gynecology. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2007. http://www.mdconsult.com/das/book/body/206003627-2/0/1524/96.html?tocnode=53759192&fromURL=96.html#4-u1.0-B978-0-323-02951-3..50018-2_472. Accessed June 16, 2010.
  4. Miltenburg DM, et al. Benign breast disease. Obstetrics and Gynecology Clinics of North America. 2008;35:285.
  5. Poggi MM, et al. The Breast. In: DeCherney AH, et al. Current Diagnosis & Treatment Obstetrics & Gynecology. 10th ed. New York, N.Y.: McGraw-Hill Medical; 2007. http://www.accessmedicine.com/content.aspx?aID=2394211. Accessed June 16, 2010.
  6. Smith RL, et al. Evaluation and management of breast pain. Mayo Clinic Proceedings. 2004;79:353.
  7. Golshan M, et al. Breast pain. http://www.uptodate.com/home/index.html. Accessed June 16, 2010.
  8. Pruthi S, et al. Vitamin E and evening primrose oil for management of cyclical mastalgia: A randomized pilot study. Alternative Medicine Reviews. 2010;15:59.
DS01070 Aug. 20, 2010

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