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Complications
By Mayo Clinic staffBesides bone fractures, severe fibrous dysplasia can lead to:
- Bone deformity. The weakened area of an affected bone can cause the bone to bend (bow). If your spine is affected, you can develop scoliosis, an abnormal curving of the spine.
- Vision and hearing loss. The nerves to your eyes and ears may be surrounded by affected bone. Severe deformity of facial bones can lead to loss of vision and hearing, a rare complication.
- Arthritis. If leg and pelvic bones are deformed, arthritis may form in the joints of those bones.
- Cancer. Rarely, an affected area of bone can become cancerous.
References
- Fibrous dysplasia. American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=A00083. Accessed May 11, 2009.
- DiCaprio MR, et al. Fibrous dysplasia. Pathophysiology, evaluation, and treatment. The Journal of Bone & Joint Surgery. 2005;87:1848.
- Leet AI, et al. Current approach to fibrous dysplasia of bone and McCune-Albright syndrome. Journal of Children's Orthopaedics. 2007;1:3.
- Polyostotic fibrous dysplasia. Craniofacial & Skeletal Diseases Branch, Division of Intramural Research, National Institute of Dental and Craniofacial Research. http://csdb.nidr.nih.gov/frame_clinical_bkg.htm. Accessed May 11, 2009.
- Glorieux FH, et al. Medical therapy of children with fibrous dysplasia. Journal of Bone and Mineral Research. 2006;21(suppl):P110.
- Chapurlat RD, et al. Fibrous dysplasia of bone and McCune-Albright syndrome. Best Practice & Research Clinical Rheumatology. 2008;22:55.
