Focused ultrasound surgery for uterine fibroids




Reprints

A single copy of this article may be reprinted for personal, noncommercial use only.

Focused ultrasound surgery for uterine fibroids

By Mayo Clinic staff

Original Article:  http://www.mayoclinic.com/health/focused-ultrasound-surgery/MY00503
The Mayo Clinic Diet Book, learn more

Free

E-newsletter

Subscribe to Housecall

Our weekly general interest
e-newsletter keeps you up to date on a wide variety of health topics.

Sign up now

Definition

CLICK TO ENLARGE

Illustration showing focused ultrasound surgery 
Focused ultrasound surgery

Focused ultrasound surgery is a treatment option for uterine fibroids — noncancerous growths of the uterus. The procedure is noninvasive and preserves your uterus. Focused ultrasound surgery — also called focused ultrasound ablation — is performed while you're inside a magnetic resonance (MR) scanner equipped with a high-energy ultrasound transducer for treatment.

During the procedure, MR images give your doctor the precise location of the uterine fibroids to be treated and the locations of nearby structures, such as the bowel and bladder, to be avoided. Then the ultrasound transducer is used to send focused sound waves (sonications) into the fibroid to heat and destroy small areas of tissue. A pelvic magnetic resonance imaging (MRI) scan is typically performed before treatment to determine whether you're a good candidate for focused ultrasound surgery.

Why it's done

Focused ultrasound surgery is performed to ease bothersome symptoms associated with uterine fibroids, including heavy bleeding and pelvic pain and pressure. The procedure provides a noninvasive alternative to surgical treatment of fibroids.

Although focused ultrasound surgery offers many advantages over other fibroid treatment options, it's not the best option for everyone. It may not be a good choice for you if your fibroids are located behind heat-sensitive organs, such as your bowel. This treatment isn't intended for women who desire a future pregnancy. Long-term effects on a woman's ability to become pregnant and carry a fetus to term have not been studied adequately yet; however, a number of women have had successful pregnancies after treatment.

Risks

Rarely, MR-guided focused ultrasound may result in:

  • Burns to the skin on your abdomen
  • Damage to tissues and structures near the fibroid targeted for treatment
  • Severe discomfort or pain during the procedure

Other drawbacks of MR-guided focused ultrasound surgery include:

  • Some fibroids may not be able to be treated
  • May require further treatment if your symptoms return
  • Lacks long-term data on safety and effectiveness
  • Not widely available, as it's limited to specialized clinics
  • Not an option for women who want to optimize chance of a future pregnancy

How you prepare

A doctor performs focused ultrasound surgery in an MR scanning room. It's an outpatient procedure. You'll be asked to fast the day of the treatment. You'll also need to shave your lower abdomen between your pubic bone and bellybutton just before the treatment.

At the hospital, you're given a gown and robe to wear. Before entering the MR scanning room, remove all accessories — watch, jewelry, hairpins, wigs, dentures and hearing aids — that may contain metal or electronics. Metal objects may interfere with the magnetic field used during the exam, affecting the quality of the MR images. The magnetic field may also damage electronic items. Be sure to tell the technologist if you have any metal or electronic devices inside your body as well — metallic joint prostheses, artificial heart valves, implanted electronic devices, cochlear implants, body piercings or magnets in your dentures (most dental fillings don't cause a problem). The presence of metal inside your body may be a safety hazard or affect a portion of the MR image.

Shortly before the procedure begins, an intravenous line will be placed in one of your veins, usually on the back of your hand. The doctor or nurse will use this line to give you medication and to inject contrast material for MR images taken right after the treatment. The medication helps you relax, but you'll be awake during the procedure (conscious sedation).

You'll also have a urinary catheter inserted into your bladder. This is done to keep the bladder stable during your treatment.

What you can expect

Typically, it takes 50 to 80 sonications during a treatment session to destroy the core of a fibroid. However, depending on the size and number of fibroids you have, more sonications or a second treatment may be necessary. As your treatment progresses, the MR images allow doctors to evaluate the effects and define areas that need additional treatment. In the future, improved technology may shorten the length of each treatment and reduce the number of sessions required.

During the procedure
During the procedure, you lie on your stomach on a movable table that slides into the opening of the MR imaging scanner. A technologist makes sure that you're comfortable inside the scanner. He or she leaves the room and monitors you from an adjoining room. You'll be able to talk with him or her by microphone. Because the internal part of the magnet produces repetitive tapping, thumping sounds and other noises, earplugs will be provided to help block your noise perception.

The treatment itself takes about three to four hours, but can vary depending on the size and number of fibroids you have.

Before any ultrasound sonications are delivered, you'll be given medication intravenously to help you relax and relieve possible heat and cramping discomfort. After each sonication, you will be asked about your level of discomfort so that your medication can be adjusted or other necessary changes can be made.

Each sonication lasts approximately 20 seconds. While each portion of the fibroid is heated, MR imaging is used to monitor tissue temperature and determine if the fibroid has been heated enough to achieve the desired results. The process is repeated until most of the fibroid has reached a temperature that should destroy the tissue.

After the procedure
After the procedure, your body naturally absorbs a small portion of the ablated tissue over a period of months. Fibroid-related symptoms usually subside or improve significantly in three to six months.

If you live within a short distance (usually about 40 miles) of the medical facility, you should be able to go home as soon as you've rested for a short time after the procedure. If you're farther from home, you can arrange to stay in town and return home on the following day. You'll need a friend or family member to be with you and drive for the first 24 hours after your treatment, due to the medications you receive during the treatment.

When you get home, you can resume your normal daily activities. Although rare, pain near the treatment area, nausea and skin burns have been reported after focused ultrasound surgery in some cases. Because the procedure is so new, some complications and side effects may still be unknown.

Results

More than 70 percent of women experience significant improvement in the severity of their fibroid-related symptoms within the first three to six months after focused ultrasound surgery. Researchers also report symptom relief for up to 24 months — the longest follow-up period to date.

There have been reports of successful pregnancies following focused ultrasound surgery, but more research is needed. In the meantime, doctors don't recommend focused ultrasound surgery for any woman who plans on future pregnancy.

References
  1. Hudson SB, et al. Magnetic resonance-guided focused ultrasound surgery. Clinical Obstetrics and Gynecology. 2008;51:159.
  2. Haney AF. Leiomyomata. In: Gibb RS, et al. Danforth's Obstetrics and Gynecology. 10th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins; 2008:916.
  3. The American College of Obstetrics and Gynecologists. Alternatives to hysterectomy in the management of leiomyomas. Obstetrics & Gynecology. 2008;112:387.
  4. Hesley GK, et al. Noninvasive treatment of uterine fibroids: Early Mayo Clinic experience with magnetic resonance imaging-guided focused ultrasound. Mayo Clinic Proceedings. 2006;81:936.
  5. Stewart EA, et al. Sustained relief of leiomyoma symptoms by using focused ultrasound surgery. Obstetrics & Gynecology. 2007;110:279.
  6. Stewart EA, et al. Clinical outcomes of focused ultrasound surgery for the treatment of uterine fibroids. Fertility and Sterility. 2006;85:22.
  7. Fennessy FM, et al. Uterine leiomyomas: MR imaging-guided focused ultrasound surgery - Results of different treatment protocols. Radiology. 2007;243:885.
  8. Funaki K, et al. Clinical outcomes of magnetic resonance-guided focused ultrasound surgery for uterine myomas: 24-month follow-up. Ultrasound in Obstetrics & Gynecology. 2009;34:584.
  9. Rabinovici J, et al. Pregnancy outcome after magnetic resonance-guided focused ultrasound surgery (MRgFUS) for conservative treatment of uterine fibroids. Fertility and Sterility. 2010;1:199.
MY00503 March 31, 2011

© 1998-2013 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

  • Reprints
  • Print
  • Share on:

  • Email

Advertisement


Text Size: smaller largerlarger