Foot drop

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Causes

By Mayo Clinic staff

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Illustration of peroneal nerve 
Peroneal nerve

Foot drop is caused by weakness or paralysis of the muscles below the knee involved in lifting the front part of the foot. The underlying causes of foot drop are varied. Often, neurological, muscular and anatomical problems overlap.

Specific foot drop causes may include:

  • Muscle or nerve damage. An injury to the muscles that control the ankle and toes can cause foot drop. Sometimes nerve damage — from an injury to the nerves in the lower spine or leg to the long-term nerve damage of diabetes (neuropathy) — causes foot drop. In other cases, nerve damage occurs during hip or knee replacement surgery. Pressure to the nerve on the outside of the shinbone just below the knee (peroneal or fibular nerve), as you might experience if you sit with your legs crossed for too long, can trigger temporary foot drop.
  • Muscle or nerve disorders. Various forms of muscular dystrophy, an inherited disease that causes progressive muscle weakness, may contribute to foot drop. Various forms of compartment syndrome, a condition characterized by the compression of nerves and blood vessels within an enclosed space, may have the same effect.
  • Central nervous system disorders. Disorders that affect the spinal cord or brain — such as amyotrophic lateral sclerosis (ALS), multiple sclerosis or stroke — may cause foot drop.
References
  1. Stewart JD. Foot drop: Where, why and what to do? Practical Neurology. 2008;8:158.
  2. Tural S, et al. Foot drop: The first sign of an intracranial tumor? Journal of Clinical Neuroscience. 2007;14:490.
  3. Ropper AH, et al. Disorders of stance and gait. In: Ropper AH, et al. Adams & Victor's Principles of Neurology. 9th ed. New York, N.Y.: McGraw-Hill Medical; 2009. http://www.accessmedicine.com/content.aspx?aid=3630849. Accessed Sept. 21, 2009.
  4. NINDS foot drop information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/foot_drop/foot_drop.htm. Accessed Sept. 21, 2009.
  5. Sackley C, et al. Rehabilitation interventions for foot drop in neuromuscular disease (Review). Cochrane Database of Systematic Reviews. 2009:CD003908.

DS01031

Nov. 5, 2009

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