Galactorrhea

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Symptoms

By Mayo Clinic staff

Signs and symptoms associated with galactorrhea include:

  • Persistent or intermittent milky nipple discharge that has no trace of blood
  • Spontaneously leaked or manually expressed nipple discharge
  • One or both breasts affected
  • Absent or irregular menstrual periods
  • Headaches or vision problems

When to see a doctor
If you have a persistent milky nipple discharge from one or both of your breasts and you're not pregnant or breast-feeding, make an appointment to see your doctor.

If breast stimulation triggers nipple discharge from multiple ducts, there is little cause for worry. The discharge probably doesn't signal breast cancer, but you should still see a doctor for evaluation.

Nonmilky nipple discharge — particularly if the discharge is bloody, yellow or clear and is occurring from one duct — requires urgent medical evaluation, as it may be a sign of an underlying breast cancer.

References
  1. Lobo RA. Hyperprolactinemia, galactorrhea, and pituitary adenomas: Etiology,
  2. differential diagnosis, natural history, management. In: Katz VL, et al., eds. Comprehensive Gynecology. 5th ed. Philadelphia, Pa.: Mosby; 2007. http://www.mdconsult.com/das/book/body/202383887-3/1002403495/1524/257.html#4-u1.0-B978-0-323-02951-3..50042-X_1261. Accessed May 24, 2010.
  3. Ferri FF. Galactorrhea. In: Ferri FF. Ferri's Clinical Advisor 2010. St. Louis, Mo.: Mosby; 2009. http://www.mdconsult.com/das/book/body/202383887-3/1002403495/2088/252.html#4-u1.0-B978-0-323-05609-0..00016-2--sc0010_5179. Accessed May 24, 2010.
  4. Snyder PJ. Causes of hyperprolactinemia. http://www.uptodate.com/home/index.html. Accessed May 24, 2010.
  5. Mancini T, et al. Hyperprolactinemia and Prolactinomas. Endocrinology and Metabolism Clinics of North America. 2008;37:67.
  6. Snyder PJ. Clinical manifestations and diagnosis of hyperprolactinemia. http://www.uptodate.com/home/index.html. Accessed May 24, 2010.
  7. Snyder PJ. Treatment of hyperprolactinemia due to lactotroph adenoma and other causes. http://www.uptodate.com/home/index.html. Accessed May 24, 2010.
  8. Iglehart JD. Diseases of the breast. In: Townsend CM, et al. Sabiston Textbook of Surgery. 18th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/202388075-8/0/1565/325.html?tocnode=54737836&fromURL=325.html#4-u1.0-B978-1-4160-3675-3..X5001-1--section7_1642. Accessed May 24, 2010.
  9. Pruthi S (expert opinion). Mayo Clinic, Rochester, Minn. June 3, 2010.
  10. Nippoldt TB (expert opinion). Mayo Clinic, Rochester, Minn. June 8, 2010.
DS00761 July 22, 2010

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