Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get StartedDefinition
By Mayo Clinic staffGamma-knife radiosurgery treats a variety of structural abnormalities inside the brain by applying intersecting beams of radiation to the abnormal area. Gamma-knife radiosurgery is often a safer option than traditional neurosurgery because no incisions are involved.
In gamma-knife radiosurgery, doctors use advanced imaging technology to localize tumors and vascular abnormalities in the brain with pinpoint accuracy, so an array of radiation beams can be focused precisely on the target from many different directions.
Each individual radiation beam is too weak to harm the brain tissue it passes through. The effect of gamma-knife radiosurgery occurs only at the spot in the brain where all the beams meet. With the help of a computer, this spot can be accurately plotted to within a fraction of a millimeter.
Why it's done- Stereotactic radiosurgery. American Association of Neurological Surgeons. http://www.neurosurgerytoday.org/what/patient_e/stereotactic.asp. Accessed July 31, 2008.
- Barbara Woodward Lips Patient Education Center. Radiosurgery Using the Gamma Knife. Rochester, Minn.: Mayo Foundation for Medical Education and Research. 2006.
- Gamma Knife. Radiological Society of North America. http://www.radiologyinfo.org/en/info.cfm?pg=gamma_knife. Accessed July 31, 2008.
- Chen CC, et al. Stereotactic cranial radiosurgery and radiotherapy. http://www.uptodate.com/home/index.html. Accessed July 31, 2008.
- Wen PY, et al. Treatment of brain metastases in favorable prognosis patients. http://www.uptodate.com/home/index.html. Accessed Aug. 1, 2008.
- Singer RJ, et al. Brain arteriovenous malformations. http://www.uptodate.com/home/index.html. Accessed Aug. 1, 2008.
- Zahid BH, et al. Trigeminal neuralgia. http://www.uptodate.com/home/index.html. Accessed Aug. 1, 2008.
- Park JK, et al. Acoustic neuroma. http://www.uptodate.com/home/index.html. Accessed Aug. 1, 2008.
- Abram S, et al. Stereotactic radiation techniques in the treatment of acoustic schwannomas. Otolaryngologic Clinics of North America. 2007;40(3):571-588.
- PituitaryFAQs, Pituitary Network Association. http://www.pituitary.org/faq/. Accessed Aug. 1, 2008.
- Stereotactic Radiosurgery for Patients with Pituitary Adenomas. Harrisburg, Pa. International RadioSurgery Association. http://www.irsa.org/Pituitary%20Guideline.pdf. Accessed Aug. 1, 2008.
- Kavanagh G, et al. Complications of cranial stereotactic radiosurgery. http://www.uptodate.com/home/index.html. Accessed Aug. 1, 2008.
- Stereotactic Radiosurgery. Radiological Society of North America. http://www.radiologyinfo.org/en/info.cfm?PG=stereotactic&bhcp=1. Accessed Aug. 1, 2008.
- Link M. (expert opinion). Mayo Clinic, Rochester, Minn. Aug. 7, 2008.