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Risk factors

By Mayo Clinic staff

Digestive Health

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Conditions that can increase your risk of GERD include:

  • Obesity
  • Hiatal hernia
  • Pregnancy
  • Smoking
  • Dry mouth
  • Asthma
  • Diabetes
  • Delayed stomach emptying
  • Connective tissue disorders, such as scleroderma
  • Zollinger-Ellison syndrome
References
  1. Ferri FF. Gastroesophageal reflux disease. In: Ferri FF. Ferri's Clinical Advisor 2011: Instant Diagnosis and Treatment.Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-05610-6..C2009-0-38600-6--TOP&isbn=978-0-323-05610-6&about=true&uniqId=230100505-53. Accessed April 13, 2011.
  2. Kahrilas PJ. Clinical manifestations and diagnosis of gastroesophageal reflux in adults. http://www.uptodate.com/home/index.html. Accessed April 13, 2011.
  3. Kahrilas PJ. Medical management of gastroesophageal reflux disease in adults. http://www.uptodate.com/home/index.html. Accessed April 13, 2011.
  4. Michelfelder AJ, et al. Integrative medicine and gastrointestinal disease. Primary Care: Clinics in Office Practice. 2010;37:255.
  5. Kiefer D. Gastroesophageal reflux disease. In: Rakel D. Integrative Medicine. 2nd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/208746819-2/0/1494/0.html. Accessed April 13, 2011.
  6. Achem SR. Noncardiac chest pain — Treatment approaches. Gastroenterology Clinics of North America. 2008;37:859.
  7. Oranu AC, et al. Noncardiac chest pain: Gastroesophageal reflux disease. Medical Clinics of North America. 2010;94:233.
  8. Kahrilas PJ, et al. American Gastroenterological Association medical position statement on the management of gastroesophageal reflux disease. Gastroenterology. 2008;135:1383.
  9. Fennerty MB, et al. Short- and long-term management of heartburn and other acid-related disorders: Development of an algorithm for primary care providers. The Journal of Family Practice. 2009;58:S1.
  10. Weight management. U. S. Department of Agriculture. http://www.nutrition.gov/nal_display/index.php?info_center=11&tax_level=3&tax_subject=390&topic_id=1741&level3_id=6295&level4_id=0&level5_id=0&placement_default=0. Accessed April 13, 2011.
  11. Picco MF (expert opinion). Mayo Clinic, Rochester, Minn. April 24, 2011.
  12. Transoral Incisionless Fundoplication. http://www.endogastricsolutions.com/esophyx_overview.htm.  Accessed March 26, 2012.
  13. Bonavina L, et al. Laparoscopic sphincter augmentation device eliminates reflux symptoms and normalizes esophageal acid exposure: one- and 2-year results of a feasibility trial. Annals of Surgery. 2010; 252: 857.
DS00967 April 13, 2012

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