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By Mayo Clinic staff
Jaundice
Gilbert syndrome can cause episodes of jaundice. However, the jaundice is usually mild and goes away on its own. There are no other known complications of the condition, and it won't damage your liver.
More side effects with certain medications
The low level of the bilirubin-processing enzyme may cause increased side effects with certain medications because this enzyme helps eliminate these medications. In particular, irinotecan (Camptosar), a medication used to treat colon cancer, can reach toxic levels if you have Gilbert syndrome, causing severe diarrhea. Because of this potential effect with certain medications, talk to your doctor before taking any new medications if you have Gilbert syndrome.