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By Mayo Clinic staffBecause Gilbert syndrome is essentially a mild, harmless condition, it doesn't require treatment. The level of jaundice associated with Gilbert syndrome is typically harmless as well, and goes away on its own.
If you have Gilbert syndrome, you don't typically need long-term monitoring of your condition or repeat blood tests. But consult your doctor if you notice worsening jaundice or other symptoms.
If you're concerned about jaundice, the barbiturate medication phenobarbital may reduce bilirubin levels but can have side effects such as sedation and lightheadedness.