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  • With Mayo Clinic endocrinologist

    Maria Collazo-Clavell, M.D.

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Mayo Clinic Health Manager

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Question

Glucosamine: Does it affect blood sugar?

Is it safe to take glucosamine if I have diabetes? I take glucosamine for mild osteoarthritis. But I recently heard that glucosamine may make it more difficult to control my blood sugar levels.

Answer

from Maria Collazo-Clavell, M.D.

Glucosamine is one of the most popular dietary supplements sold in the United States, even though study results have been mixed regarding its ability to reduce osteoarthritis pain.

Some preliminary research had suggested that glucosamine might worsen insulin resistance, which can contribute to increases in blood sugar in people with type 2 diabetes. However, subsequent studies refute these findings.

While glucosamine doesn't appear to affect blood sugar levels, talk with your doctor about potential interactions with other medications you might be taking — such as warfarin (Coumadin), a blood thinner.

Next question
MSM for arthritis pain: Is it safe?
References
  1. Dahmer S, et al. Glucosamine. American Family Physician. 2008;78:471.
  2. Glucosamine sulfate. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Sept. 11, 2009.

AN01723

Nov. 10, 2009

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