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  • With Mayo Clinic endocrinologist

    Maria Collazo-Clavell, M.D.

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Question

Glucosamine: Does it affect blood sugar?

Is it safe to take glucosamine supplements if I have diabetes?

Answer

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from Maria Collazo-Clavell, M.D.

Even though glucosamine is technically a type of sugar, it doesn't appear to affect blood glucose levels or insulin sensitivity. Some preliminary research had suggested that glucosamine might worsen insulin resistance, which can contribute to increases in blood sugar in people with type 2 diabetes. But subsequent studies refuted these findings.

Glucosamine is one of the most popular dietary supplements sold in the United States, although study results have been mixed regarding its ability to reduce osteoarthritis pain. While glucosamine doesn't appear to affect glucose levels or insulin sensitivity, the supplement can interact with other medications you might be taking — such as warfarin (Coumadin), a blood thinner.

Next question
MSM for arthritis pain: Is it safe?
References
  1. Glucosamine sulfate. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Sept. 20, 2011.
  2. Glucosamine hydrochloride. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Sept. 20, 2011.
  3. Bauer BA (expert opinion). Mayo Clinic, Rochester, Minn. Aug. 10, 2011.
  4. Lovett E, et al. Advising patients about herbs and nutraceuticals: Tips for primary care providers. Primary Care Clinics Office Practice. 2010;37:13.
AN01723 Nov. 22, 2011

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