Treatments and drugs
By Mayo Clinic staff
Gonorrhea treatment in adults
Adults with gonorrhea are treated with antibiotics. Due to emerging strains of drug-resistant Neisseria gonorrhoeae, the Centers for Disease Control and Prevention recommends that uncomplicated gonorrhea be treated only with the antibiotic ceftriaxone — given as an injection — in combination with either azithromycin or doxycycline — two antibiotics that are taken orally.
Gonorrhea treatment for partners
Your partner also should undergo testing and treatment for gonorrhea, even if he or she has no signs or symptoms. Your partner receives the same treatment you do. Even if you've been treated for gonorrhea, you can be reinfected if your partner isn't treated.
Gonorrhea treatment for babies
Babies born to mothers with gonorrhea receive a medication in their eyes soon after birth to prevent infection. If an eye infection develops, babies can be treated with antibiotics.
- Marrazzo JM, et al. Neisseria gonorrhoeae. In: Mandell JE, et al. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2010. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-443-06839-3..X0001-X--TOP&isbn=978-0-443-06839-3&uniq=208746819. Accessed Nov. 22, 2010.
- CDC fact sheet: Gonorrhea. Centers for Disease Control and Prevention. http://www.cdc.gov/std/gonorrhea/gonorrhea-fact-sheet.pdf. Accessed Nov. 22, 2010.
- Del Rio C, et al. Update to CDC's "Sexually transmitted diseases treatment guidelines, 2006:" Fluoroquinolones no longer recommended for treatment of gonococcal infections. Morbidity & Mortality Weekly Report. 2007;56:332.
- Swygard H, et al. Neisseria gonorrhoeae infections in women. http://www.uptodate.com/home/index.html. Accessed Nov. 23, 2010.
- Workowski KA, et al. Emerging antimicrobial resistance in Neisseria gonorrhoeae: Urgent need to strengthen prevention strategies. Annals of Internal Medicine. 2008;148:606.
- Holder NA. Gonococcal infections. Pediatrics in Review. 2008;29:228.
- Screening for gonorrhea: Recommendation statement. U.S. Preventive Services Task Force. http://www.uspreventiveservicestaskforce.org/uspstf05/gonorrhea/gonrs.htm. Accessed Nov. 23, 2010.
- Swygard H, et al. Neisseria gonorrhoeae infections in men. http://www.uptodate.com/home/index.html. Accessed Nov. 23, 2010.
- CDC no longer recommends oral drug for gonorrhea treatment. Centers for Disease Control and Prevention. http://www.cdc.gov/nchhstp/newsroom/2012/GCTx-Guidelines-PressRelease.html. Accessed Aug. 10, 2012.


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