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Graves' dermopathy: What causes it?

What causes Graves' dermopathy? Can it be treated?

- Carol / Massachusetts

Mayo Clinic endocrinologist and men's health specialist Todd Nippoldt, M.D., and colleagues answer select questions from readers.

Answer

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Photo of Graves' dermopathy Graves' dermopathy

Rarely, people with Graves' disease develop Graves' dermopathy, a skin condition characterized by red, swollen skin, usually on the shins and tops of the feet. The texture of the affected skin may be similar to that of an orange peel. This condition results from a buildup of protein in the skin — the cause of which isn't known. Doctors may also refer to it as thyroid dermopathy or pretibial myxedema.

Treatment of Graves' dermopathy is usually directed at the underlying Graves' disease but may also include:

  • Cortisone creams to reduce inflammation
  • Compression wraps

Early diagnosis and treatment of Graves' dermopathy can improve the chances of successful treatment. Unfortunately, even with successful treatment of the underlying Graves' disease, the dermopathy may still develop, persist and even progress.

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Jul 5, 2008