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    Todd B. Nippoldt, M.D.

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Question

Graves' dermopathy: How is it treated?

What causes Graves' dermopathy? How is it treated?

Answer

from Todd B. Nippoldt, M.D.

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Photo of Graves' dermopathy
Graves' dermopathy

Rarely, people with Graves' disease develop Graves' dermopathy, a skin condition characterized by red, swollen skin, usually on the shins and tops of the feet. The texture of the affected skin may be similar to that of an orange peel. This condition results from a buildup of certain carbohydrates in the skin — the cause of which isn't known. Doctors may also refer to it as pre-tibial myxedema.

Treatment of Graves' dermopathy is usually directed at the underlying Graves' disease but may also include:

  • Cortisone creams to reduce inflammation
  • Compression wraps

Early diagnosis and treatment of Graves' dermopathy can improve the chances of successful treatment. Unfortunately, even with successful treatment of the underlying Graves' disease, the dermopathy may still develop, persist and even progress.

Next question
Thyroid disease: Can it affect a person's mood?
References
  1. Graves' disease. U.S. Department of Health and Human Services. http://www.endocrine.niddk.nih.gov/pubs/graves/Graves.pdf. Accessed April 23, 2009.
  2. Nippoldt TB (expert opinion). Mayo Clinic, Rochester, Minn. June 3, 2009.
  3. Davies TF, et al. Thyrotoxicosis. In: Kronenberg HM, et al. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/138729846-2/0/1555/47.html?tocnode=54106586&fromURL=47.html#4-u1.0-B978-1-4160-2911-3..50013-3_849. Accessed May 21, 2009.

AN00605

July 11, 2009

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