H. pylori infection

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Complications

By Mayo Clinic staff

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Illustration showing ulcers 
Ulcers

Complications associated with H. pylori infection include:

  • Ulcers. H. pylori can damage the protective lining of your stomach and small intestine. This can allow stomach acid to create an open sore (ulcer).
  • Inflammation of the stomach lining. H. pylori infection can irritate your stomach, causing inflammation (gastritis).
  • Stomach cancer. H. pylori infection is a strong risk factor for certain types of stomach cancer.
References
  1. H. pylori and peptic ulcers. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/hpylori. Accessed March 25, 2011.
  2. Peura DA, et al. Helicobacter pylori. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229935664-2192. Accessed March 25, 2011.
  3. Crowe SE. Bacteriology and epidemiology of Helicobacter pylori infection. http://www.uptodate.com/home/index.html. Accessed March 25, 2011.
  4. Tryforos M. Helicobacter pylori infection. In: Ferri FF. Ferri's Clinical Advisor 2011: Instant Diagnosis and Treatment. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-05610-6..C2009-0-38600-6--TOP&isbn=978-0-323-05610-6&about=true&uniqId=230100505-53. Accessed March 28, 2011.
  5. Malagelada JR, et al. Acid peptic disease: Clinical manifestations, diagnosis, treatment and prognosis. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed March 28, 2011.
  6. Crowe SE. Treatment regimens for Helicobacter pylori. http://www.uptodate.com/home/index.html. Accessed March 25, 2011.
  7. Talley NJ, et al. Gastric cancer consensus conference recommends Helicobacter pylori screening and treatment in asymptomatic persons from high-risk populations to prevent gastric cancer. American Journal of Gastroenterology. 2008;103:510.
DS00958 May 24, 2011

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