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Risk factors

By Mayo Clinic staff

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Certain factors may increase your risk of developing hairy cell leukemia. Not all research studies agree on what factors increase your risk of the disease. Some research indicates that your risk of hairy cell leukemia increases based on your:

  • Exposure to radiation. People exposed to radiation, such as those who work around X-ray machines or those who received radiation treatment for cancer, may have a higher risk of developing hairy cell leukemia.
  • Exposure to chemicals. Industrial and agricultural chemicals could play a role in hairy cell leukemia development. However, some studies have found this not to be the case.
  • Exposure to sawdust. Some studies have found a link between working with wood and sawdust and an increased risk of hairy cell leukemia. But this connection hasn't been proven conclusively.
References
  1. Tallman MS, et al. Hairy cell leukemia. In: Abeloff MD. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2008:2309.
  2. Zakarija A, et al. Hairy cell leukemia. In: Hoffman R, et al. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa.: Churchill Livingstone; 2008. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-443-06715-0..X5001-8--TOP&isbn=978-0-443-06715-0&uniq=177554631. Accessed Jan. 7, 2010.
  3. Saven A. Hairy cell leukemia. In: Lichtman MA, et al. Williams Hematology. 7th ed. New York, N.Y.: McGraw-Hill; 2008. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=69. Accessed Jan. 7, 2010.
  4. Hairy cell leukemia treatment (PDQ): Patient version. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/hairy-cell-leukemia/patient/allpages/print. Accessed Jan. 7, 2010.
  5. Hairy cell leukemia treatment (PDQ): Health professional version. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/hairy-cell-leukemia/healthprofessional/allpages/print. Accessed Jan. 7, 2010.
  6. Rituxan (prescribing information). South San Francisco, Calif.: Genentech Inc.; 2009. http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/103705s5299lbl.pdf. Accessed Jan. 7, 2010.
  7. Integrative medicine & complementary and alternative therapies as part of blood cancer care. The Leukemia & Lymphoma Society. http://www.leukemia-lymphoma.org/attachments/National/br_1150734030.pdf. Jan. 7, 2010.
DS00673 Feb. 2, 2010

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