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Causes
The most common cause of hand-foot-and-mouth disease is infection due to the coxsackievirus A16. The coxsackievirus belongs to a group of viruses called nonpolio enteroviruses. Other enteroviruses sometimes cause hand-foot-and-mouth disease.
Oral ingestion is the main source of coxsackievirus infection and hand-foot-and-mouth disease. The illness spreads by person-to-person contact with nose and throat discharges, saliva, fluid from blisters, or the stool of someone with the infection. The virus can also spread through a mist of fluid sprayed into the air when someone coughs or sneezes.
Hand-foot-and-mouth disease is most common in children in child care settings because of frequent diaper changes and potty training, and because little children often put their hands in their mouths.
Although your child is most contagious with hand-foot-and-mouth disease during the first week of the illness, the virus can remain in his or her body for weeks after the signs and symptoms are gone. That means your child still can infect others.
Some people, particularly adults, can pass the virus without showing any signs or symptoms of the disease.
Outbreaks of the disease are more common in summer and autumn in the United States and other temperate climates. In tropical climates, outbreaks occur year-round.
Hand-foot-and-mouth disease isn't related to foot-and-mouth disease (sometimes called hoof-and-mouth disease), which is an infectious viral disease found in farm animals. You can't contract hand-foot-and-mouth disease from pets or other animals, and you can't transmit it to them.
- Hand, foot, & mouth disease (HFMD). Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvrd/revb/enterovirus/hfhf.htm. Accessed June 22, 2009.
- Enteroviruses - non polio. World Health Organization. http://www.who.int/mediacentre/factsheets/fs174/en/print.html. Accessed June 22, 2009.
- Hand, foot and mouth disease. American Osteopathic College of Dermatology. http://www.aocd.org/skin/dermatologic_diseases/hand_foot_mouth_disease.html. Accessed June 22, 2009.
- Non-polio enterovirus infections. Centers for Disease Control and Prevention. www.cdc.gov/ncidod/dvrd/revb/enterovirus/non-polio_entero.htm. Accessed June 26, 2009.
