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Risk factors
Hand-foot-and-mouth disease primarily affects children younger than age 10. Children in child care centers are especially susceptible to outbreaks of hand-foot-and-mouth disease because the infection spreads by person-to-person contact, and young children are the most susceptible.
Children usually develop immunity to hand-foot-and-mouth disease as they get older by building antibodies after exposure to the virus that causes the disease. However, it's possible for adolescents and adults to get the disease.
- Hand, foot, & mouth disease (HFMD): Fast facts. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvrd/revb/enterovirus/hfhf.htm. Accessed July 12, 2011.
- Ng JJ, et al. Hand-foot-mouth disease. In: Ferri FF. Ferri's Clinical Advisor 2012. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/linkTo?type=bookHome&isbn=978-0-323-05611-3&eid=4-u1.0-B978-0-323-05611-3..C2009-0-38601-8--TOP&uniq=266352183-2. Accessed July 12, 2011.
- Modlin JF. Clinical manifestations and diagnosis of enterovirus infections. http://www.uptodate.com/home/index.html. Accessed July 12, 2011.
- Non-polio enterovirus infections. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvrd/revb/enterovirus/non-polio_entero.htm. Accessed July 13, 2011.
- Belazarian L, et al. Exanthematous viral diseases. In: Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, N.Y.: The McGraw-Hill Companies; 2008. http://www.accessmedicine.com/content.aspx?aID=2997642. Accessed July 13, 2011.
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