Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get StartedTreatments and drugs
There's no specific treatment for hand-foot-and-mouth disease. Signs and symptoms of hand-foot-and-mouth disease usually clear up in seven to 10 days.
A topical oral anesthetic may help relieve the pain of mouth sores. Over-the-counter pain medications other than aspirin, such as acetaminophen (Tylenol, others) or ibuprofen (Advil, Motrin, others) may help relieve general discomfort.
- Hand, foot, & mouth disease (HFMD). Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvrd/revb/enterovirus/hfhf.htm. Accessed June 22, 2009.
- Enteroviruses - non polio. World Health Organization. http://www.who.int/mediacentre/factsheets/fs174/en/print.html. Accessed June 22, 2009.
- Hand, foot and mouth disease. American Osteopathic College of Dermatology. http://www.aocd.org/skin/dermatologic_diseases/hand_foot_mouth_disease.html. Accessed June 22, 2009.
- Non-polio enterovirus infections. Centers for Disease Control and Prevention. www.cdc.gov/ncidod/dvrd/revb/enterovirus/non-polio_entero.htm. Accessed June 26, 2009.