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Symptoms
By Mayo Clinic staffSigns and symptoms of hemolytic uremic syndrome may include:
- Bloody diarrhea
- Vomiting
- Abdominal pain
- Pale skin tone
- Fatigue and irritability
- Fever, usually not high
- Small, unexplained bruises or bleeding from the nose and mouth
- Decreased urination or blood in the urine
- Swelling of the face, hands, feet or entire body
- Confusion
Sometimes neurological symptoms, such as seizures, develop as well.
When to see a doctor
Call your doctor immediately if you or your child experiences unexplained bruises, bloody diarrhea, unusual bleeding, swollen limbs, extreme fatigue or decreased urine output after several days of diarrhea. Seek emergency care if you or your child doesn't urinate for 12 hours or more.
- Hemolytic uremic syndrome in children. National Institutes of Diabetes and Digestive and Kidney Diseases. http://kidney.niddk.nih.gov/kudiseases/pubs/childkidneydiseases/hemolytic_uremic_syndrome/hemolyticuremic.pdf. Accessed Oct. 22, 2010.
- Piercefield EW, et al. Hemolytic uremic syndrome after an Escherichia coli O111 outbreak. Archives of Internal Medicine. 2010;170:1656.
- Thrombotic thrombocytopenic purpura and hemolytic-uremic syndrome. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec11/ch133/ch133g.html. Accessed Oct. 22, 2010.
- George JN. Causes of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome in adults. http://www.uptodate.com/home/index.html. Accessed Oct. 22, 2010.
- Niaudet P. Clinical manifestations and diagnosis of Shiga-like toxin associated (typical) hemolytic uremic syndrome in children. http://www.uptodate.com/home/index.html. Accessed Oct. 22, 2010.
- Noris M, et al. Atypical hemolytic-uremic syndrome. New England Journal of Medicine. 2009;361:1676.
- Foodborne illness: Frequently asked questions. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dbmd/diseaseinfo/files/foodborne_illness_FAQ.pdf. Accessed Oct. 22, 2010.
- Elliott MM, et al. Interventions for haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura (Review). Cochrane Database Systematic Reviews. 2009:CD003595.http://www2.cochrane.org/reviews. Accessed Oct. 22, 2010.
- Scheiring J, et al. Today's understanding of the haemolytic uraemic syndrome. European Journal of Pediatrics. 2010;169:17.
- Nast CC, et al. Thrombotic microangiopathies. In: Lerma EV, et al. Current Diagnosis & Treatment: Nephrology & Hypertension. New York, N.Y.: The McGraw Hill Companies; 2009. http://www.accessmedicine.com/content.aspx?aID=6336929. Accessed Oct. 22, 2010.
- Pigott DC. Foodborne illness. Emergency Medical Clinics of North America. 2008;26:475.
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