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Treatments and drugs
By Mayo Clinic staffHenoch-Schonlein purpura usually improves on its own within four to six weeks with no lasting ill effects. Treatment is usually aimed at relieving discomfort and preventing complications. Most often, this means bed rest, plenty of fluids and, occasionally, nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin, others).
In certain circumstances, children and young adults with Henoch-Schonlein purpura may require hospitalization. This is likely if they have:
- Trouble staying well hydrated
- Severe abdominal pain or gastrointestinal bleeding
- Joint symptoms that make movement difficult
- Serious kidney problems
Corticosteroids
The use of powerful corticosteroids in treating or preventing complications of Henoch-Schonlein purpura is controversial. Because these drugs can have serious side effects and their usefulness isn't clear, be sure to discuss the risks and benefits with your doctor or pediatrician.
- Kraft DM, et al. Henoch-Schonlein purpura: A review. American Academy of Family Physicians. http://www.aafp.org/afp/980800ap/kraft.html. Accessed Aug. 10, 2008.
- Dedeoglu F, et al. Management of Henoch-Schonlein purpura. http://www.uptodate.com/home/index.html. Accessed Aug. 10, 2008.
- Dedeoglu F, et al. Clinical manifestations and diagnosis of Henoch-Schonlein purpura. http://www.uptodate.com/home/index.html. Aug. 17, 2008.
- Gibson KL, et al. Corticosteroid therapy for Henoch-Schonlein purpura. Pediatrics. 2008;121(4):870-871.
- Henoch-Schonlein purpura. Vasculitis Foundation. http://www.vasculitisfoundation.org/HenochSchonleinpurpura. Accessed Aug. 10, 2008.
- Weiss PF, et al. Effects of corticosteroid on Henoch-Schonlein purpura: A systematic review. Pediatrics. 2007;120(5):1079-1087.
- Henoch-Schonlein Purpura. National Kidney and Urologic Diseases Clearinghouse. http://kidney.niddk.nih.gov/kudiseases/pubs/HSP. Accessed Aug. 10, 2008.
