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Central-acting agents, also called central adrenergic inhibitors, treat several conditions, including high blood pressure, drug and alcohol withdrawal, and hot flashes. Find out more about these medications.By Mayo Clinic staff
Central-acting agents lower your heart rate and reduce your blood pressure. They work by preventing your brain from sending signals to your nervous system to speed up your heart rate and narrow your blood vessels. As a result, your heart doesn't pump as hard and your blood flows more easily through your blood vessels.
Examples of central-acting agents
Central-acting agents are also called central adrenergic inhibitors, central alpha agonists and central agonists. Several central-acting agents are available. Which one is best for you depends on your health and the condition being treated.
Examples of central-acting agents include:
- Clonidine (Catapres)
- Guanfacine (Tenex)
(1 of 2)
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- Types of blood pressure medications. American Heart Association. http://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Types-of-Blood-Pressure-Medications_UCM_303247_Article.jsp. Accessed Sept. 30, 2010.
- High blood pressure: Medicines to help you. U.S. Food and Drug Administration. http://www.fda.gov/forconsumers/byaudience/forwomen/ucm118594.htm. Accessed Sept. 30, 2010.
- Kaplan NM, et al. Indications and contraindications to the use of specific antihypertensive drugs. http://www.uptodate.com/home/index.html. Accessed Sept. 30, 2010.
- Chobanian AV, et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. New England Journal of Medicine. 2003;289:2560.