High blood pressure (hypertension)

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continued:

Central-acting agents

Uses for central-acting agents

Doctors prescribe central-acting agents to prevent, treat or improve symptoms in conditions, such as:

  • High blood pressure
  • Hot flashes
  • Alcohol or drug withdrawal
  • Attention-deficit/hyperactivity disorder (ADHD)
  • Tourette syndrome

Side effects and cautions

These medications can have strong side effects, so they aren't commonly used. Side effects include:

  • Extreme fatigue
  • Drowsiness or sedation
  • Dizziness
  • Impotence
  • Constipation
  • Dry mouth
  • Headache
  • Weight gain
  • Psychological problems, such as depression

Abruptly stopping use of some central-acting agents can cause a sudden, dangerous increase in blood pressure. Don't stop taking these medications, especially if you are taking a beta blocker, without talking to your doctor.

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References
  1. Flynn JT. Treatment of high blood pressure: Drug therapy. In: Kaplan NM, et al. Kaplan's Clinical Hypertension. 10th ed. Philadelphia, Pa.: Wolters Kluwer Health Lippincott Williams & Wilkins; 2010:192.
  2. Types of blood pressure medications. American Heart Association. http://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Types-of-Blood-Pressure-Medications_UCM_303247_Article.jsp. Accessed Sept. 30, 2010.
  3. High blood pressure: Medicines to help you. U.S. Food and Drug Administration. http://www.fda.gov/forconsumers/byaudience/forwomen/ucm118594.htm. Accessed Sept. 30, 2010.
  4. Kaplan NM, et al. Indications and contraindications to the use of specific antihypertensive drugs. http://www.uptodate.com/home/index.html. Accessed Sept. 30, 2010.
  5. Chobanian AV, et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. New England Journal of Medicine. 2003;289:2560.
HI00056 Dec. 16, 2010

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