High blood pressure (hypertension)

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Causes

By Mayo Clinic staff

There are two types of high blood pressure.

Primary (essential) hypertension
For most adults, there's no identifiable cause of high blood pressure. This type of high blood pressure, called essential hypertension or primary hypertension, tends to develop gradually over many years.

Secondary hypertension
Some people have high blood pressure caused by an underlying condition. This type of high blood pressure, called secondary hypertension, tends to appear suddenly and cause higher blood pressure than does primary hypertension. Various conditions and medications can lead to secondary hypertension, including:

  • Kidney problems
  • Adrenal gland tumors
  • Certain defects in blood vessels you're born with (congenital)
  • Certain medications, such as birth control pills, cold remedies, decongestants, over-the-counter pain relievers and some prescription drugs
  • Illegal drugs, such as cocaine and amphetamines
References
  1. Chobanian AV, et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. New England Journal of Medicine. 2003;289:2560.
  2. High blood pressure causes. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4603. Accessed June 8, 2010.
  3. High blood pressure, Factors that contribute to. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4650. Accessed June 8, 2010.
  4. Kaplan NM, et al. Treatment of hypertension in blacks. http://www.uptodate.com/index. Accessed June 8, 2010.
  5. Wang TJ, et al. Vitamin D deficiency and risk of cardiovascular disease. Circulation. 2008;117:503.
  6. Kaplan NM, et al. Prehypertension and borderline hypertension. http://www.uptodate.com/index. Accessed June 8, 2010.
  7. Calhoun DA, et al. Resistant hypertension: Diagnosis, evaluation and treatment. A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Hypertension. 2008;117:e510.
  8. Blood pressure-lowering drugs. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=159. Accessed June 8, 2010.
  9. Lopez L, et al. Lifestyle modification counseling for hypertensive patients: Results from the National Health and Nutrition Examination Survey 1999-2004. American Journal of Hypertension. 2009;22:325.
  10. Villegas R, et al. The cumulative effect of core lifestyle behaviours on the prevalence of hypertension and dyslipidemia. BMC Public Health. 2008;8:210.
  11. Your guide to lowering blood pressure with DASH. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/public/heart/hbp/dash/new_dash.pdf. Accessed June 8, 2010.
  12. Appel LJ, et al. Dietary approaches to prevent and treat hypertension: A scientific statement from the American Heart Association. Hypertension. 2006;47:296.
  13. Pandic S, et al. Device-guided breathing exercises in the treatment of hypertension — perceptions and effects. CVD Prevention and Control. 2008;3:163.
  14. Natural medicines in the clinical management of hypertension. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed April 28, 2010.
  15. Home blood pressure monitoring. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=576. Accessed March 9, 2010.
  16. Dietary Guidelines for Americans, 2010. U.S. Department of Health and Human Services. http://www.cnpp.usda.gov/DGAs2010-PolicyDocument.htm. Accessed Feb. 18, 2011. 
  17. U.S. Preventive Services Task Force. Screening for high blood pressure: U.S. Preventive Services Task Force reaffirmation recommendation statement. Annals of Internal Medicine. 2007;147:783.
  18. Mayo Clinic statement: Aliskiren safety concern. Mayo Pharmaceutical Formulary Committee. http://mayoweb.mayo.edu/mfpfc-cmte/1112aliskirenStatement.pdf. Accessed Dec. 23, 2011.
  19. Novartis announces termination of ALTITUDE study with Rasilez/Tekturna in high-risk patients with diabetes and renal impairment. Novartis International AG. http://www.novartis.com/downloads/newsroom/rasilez-tekturna-information-center/20111220-rasilez-tekturna.pdf. Accessed Jan. 9, 2012.
DS00100 Jan. 24, 2012

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