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Complications
By Mayo Clinic staffThe excessive pressure on your artery walls caused by high blood pressure can damage your blood vessels, as well as organs in your body. The higher your blood pressure and the longer it goes uncontrolled, the greater the damage.
Uncontrolled high blood pressure can lead to:
- Heart attack or stroke. High blood pressure can cause hardening and thickening of the arteries (atherosclerosis), which can lead to a heart attack, stroke or other complications.
- Aneurysm. Increased blood pressure can cause your blood vessels to weaken and bulge, forming an aneurysm. If an aneurysm ruptures, it can be life-threatening.
- Heart failure. To pump blood against the higher pressure in your vessels, your heart muscle thickens. Eventually, the thickened muscle may have a hard time pumping enough blood to meet your body's needs, which can lead to heart failure.
- Weakened and narrowed blood vessels in your kidneys. This can prevent these organs from functioning normally.
- Thickened, narrowed or torn blood vessels in the eyes. This can result in vision loss.
- Metabolic syndrome. This syndrome is a cluster of disorders of your body's metabolism — including increased waist circumference, high triglycerides, low high-density lipoprotein (HDL), or "good," cholesterol, high blood pressure, and high insulin levels. If you have high blood pressure, you're more likely to have other components of metabolic syndrome. The more components you have, the greater your risk of developing diabetes, heart disease or stroke.
- Trouble with memory or understanding. Uncontrolled high blood pressure also may affect your ability to think, remember and learn. Trouble with memory or understanding concepts is more common in people who have high blood pressure.
References
- Chobanian AV, et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. New England Journal of Medicine. 2003;289:2560.
- High blood pressure causes. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4603. Accessed June 8, 2010.
- High blood pressure, Factors that contribute to. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4650. Accessed June 8, 2010.
- Kaplan NM, et al. Treatment of hypertension in blacks. http://www.uptodate.com/index. Accessed June 8, 2010.
- Wang TJ, et al. Vitamin D deficiency and risk of cardiovascular disease. Circulation. 2008;117:503.
- Kaplan NM, et al. Prehypertension and borderline hypertension. http://www.uptodate.com/index. Accessed June 8, 2010.
- Calhoun DA, et al. Resistant hypertension: Diagnosis, evaluation and treatment. A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Hypertension. 2008;117:e510.
- Blood pressure-lowering drugs. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=159. Accessed June 8, 2010.
- Lopez L, et al. Lifestyle modification counseling for hypertensive patients: Results from the National Health and Nutrition Examination Survey 1999-2004. American Journal of Hypertension. 2009;22:325.
- Villegas R, et al. The cumulative effect of core lifestyle behaviours on the prevalence of hypertension and dyslipidemia. BMC Public Health. 2008;8:210.
- Your guide to lowering blood pressure with DASH. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/public/heart/hbp/dash/new_dash.pdf. Accessed June 8, 2010.
- Appel LJ, et al. Dietary approaches to prevent and treat hypertension: A scientific statement from the American Heart Association. Hypertension. 2006;47:296.
- Pandic S, et al. Device-guided breathing exercises in the treatment of hypertension — perceptions and effects. CVD Prevention and Control. 2008;3:163.
- Natural medicines in the clinical management of hypertension. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed April 28, 2010.
- Home blood pressure monitoring. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=576. Accessed March 9, 2010.
- Dietary Guidelines for Americans, 2010. U.S. Department of Health and Human Services. http://www.cnpp.usda.gov/DGAs2010-PolicyDocument.htm. Accessed Feb. 18, 2011.
- U.S. Preventive Services Task Force. Screening for high blood pressure: U.S. Preventive Services Task Force reaffirmation recommendation statement. Annals of Internal Medicine. 2007;147:783.
- Mayo Clinic statement: Aliskiren safety concern. Mayo Pharmaceutical Formulary Committee. http://mayoweb.mayo.edu/mfpfc-cmte/1112aliskirenStatement.pdf. Accessed Dec. 23, 2011.
- Novartis announces termination of ALTITUDE study with Rasilez/Tekturna in high-risk patients with diabetes and renal impairment. Novartis International AG. http://www.novartis.com/downloads/newsroom/rasilez-tekturna-information-center/20111220-rasilez-tekturna.pdf. Accessed Jan. 9, 2012.
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