The Mayo Clinic Diet Book, learn more

Free

E-newsletter

Subscribe to Housecall

Our weekly general interest
e-newsletter keeps you up to date on a wide variety of health topics.

Sign up now

Risk factors

By Mayo Clinic staff

The chances of developing histoplasmosis symptoms increase with the number of spores you inhale. Professions with a higher likelihood of spore exposure include:

  • Farmers
  • Pest control workers
  • Poultry keepers
  • Construction workers
  • Roofers
  • Landscapers and gardeners

Most at risk of severe infection
Very young children and older adults have weaker immune systems, so they're more likely to develop disseminated histoplasmosis — the most serious form of the disease. Other factors that can weaken your immune system include:

  • HIV or AIDS
  • Cancer chemotherapy
  • Corticosteroid drugs, such as prednisone
  • TNF inhibitors, often used to control rheumatoid arthritis
  • Medications that prevent rejection of organ transplants
Complications Causes
References
  1. Histoplasmosis. Centers for Disease Control and Prevention. http://www.cdc.gov/nczved/divisions/dfbmd/diseases/histoplasmosis. Accessed Dec. 20, 2011.
  2. Kaufman CA. Histoplasmosis. In: Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Dec. 20, 2011.
  3. Wheat J, et al. Pathogenesis and clinical features of pulmonary histoplasmosis. http://www.uptodate.com/home/index.html. Accessed Dec. 20, 2011.
  4. Hage CH, et al. Histoplasmosis: Introduction. In: Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Dec. 20, 2011.
  5. Fort GG, et al. Histoplasmosis. In: Ferri FF. Ferri's Clinical Advisor 2012: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-323-05611-3..C2009-0-38601-8--TOP&isbn=978-0-323-05611-3&uniqId=291436269-101. Accessed Dec. 20, 2011.
  6. Davies SF, et al. Fungal infections: Histoplasmosis. In: Mason RJ, et al. Murray and Nadel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/das/book/body/192068760-2/0/1288/0.html. Accessed Dec. 20, 2011.
  7. Histoplasmosis: Protecting workers at risk. Centers for Disease Control and Prevention. http://www.cdc.gov/niosh/docs/2005-109. Accessed Dec. 20, 2011.
  8. What is ARDS? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/ards. Accessed Dec. 20, 2011.
  9. Van Duin D. Histoplasmosis. In: Bope ET, et al. Conn's Current Therapy. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4377-0986-5..C2009-0-38984-9--TOP&isbn=978-1-4377-0986-5&about=true&uniqId=236797353-5. Accessed Dec. 20, 2011.
DS00517 Feb. 8, 2012

© 1998-2013 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

  • Reprints
  • Print

  • Share on:

  • Email

Advertisement


Text Size: smaller largerlarger