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Treatments and drugs

By Mayo Clinic staff

Treatment usually isn't necessary if you have a mild case of histoplasmosis. But if your symptoms are severe or if you have the chronic or disseminated forms of the disease, you'll likely need treatment with one or more antifungal drugs. Some of these medications come in pill form, but the strongest varieties are administered intravenously.

References
  1. Histoplasmosis. Centers for Disease Control and Prevention. http://www.cdc.gov/nczved/divisions/dfbmd/diseases/histoplasmosis. Accessed Dec. 20, 2011.
  2. Kaufman CA. Histoplasmosis. In: Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Dec. 20, 2011.
  3. Wheat J, et al. Pathogenesis and clinical features of pulmonary histoplasmosis. http://www.uptodate.com/home/index.html. Accessed Dec. 20, 2011.
  4. Hage CH, et al. Histoplasmosis: Introduction. In: Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Dec. 20, 2011.
  5. Fort GG, et al. Histoplasmosis. In: Ferri FF. Ferri's Clinical Advisor 2012: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-323-05611-3..C2009-0-38601-8--TOP&isbn=978-0-323-05611-3&uniqId=291436269-101. Accessed Dec. 20, 2011.
  6. Davies SF, et al. Fungal infections: Histoplasmosis. In: Mason RJ, et al. Murray and Nadel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/das/book/body/192068760-2/0/1288/0.html. Accessed Dec. 20, 2011.
  7. Histoplasmosis: Protecting workers at risk. Centers for Disease Control and Prevention. http://www.cdc.gov/niosh/docs/2005-109. Accessed Dec. 20, 2011.
  8. What is ARDS? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/ards. Accessed Dec. 20, 2011.
  9. Van Duin D. Histoplasmosis. In: Bope ET, et al. Conn's Current Therapy. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4377-0986-5..C2009-0-38984-9--TOP&isbn=978-1-4377-0986-5&about=true&uniqId=236797353-5. Accessed Dec. 20, 2011.
DS00517 Feb. 8, 2012

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