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Risk factors

By Mayo Clinic staff

HPV infections are common. Risk factors for HPV infection include:

  • Number of sexual partners. The greater your number of sexual partners, the more likely you are to contract a genital HPV infection. Having sex with a partner who has had multiple sex partners also increases your risk.
  • Age. Common warts occur most often in children and adolescents. While plantar warts may occur in adults, they're more likely to initially surface in childhood. Genital warts occur most often in adolescents and young adults.
  • Weakened immune systems. People who have weakened immune systems are at greater risk of HPV infections. Immune systems can be weakened by HIV/AIDS or by immune system-suppressing drugs used after organ transplants.
  • Damaged skin. Areas of skin that have been punctured or opened are more prone to develop common warts. For example, people who bite their fingernails are more likely to develop warts around their fingernails.
References
  1. Douglas JM. Papillomavirus. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4160-2805-5..50401-8&isbn=978-1-4160-2805-5&sid=1100799163&type=bookPage§ionEid=4-u1.0-B978-1-4160-2805-5..50401-8--cesec10&uniqId=230895620-4#4-u1.0-B978-1-4160-2805-5..50401-8--cesec10. Accessed Jan. 3, 2011.
  2. Habif TP. Warts. In: Habif TP. Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 5th ed. Edinburgh, U.K.; New York, N.Y.: Mosby Elsevier; 2010. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-0-7234-3541-9..00021-3&isbn=978-0-7234-3541-9&sid=1100799163&type=bookPage§ionEid=4-u1.0-B978-0-7234-3541-9..00021-3--s0015&uniqId=230895620-4#4-u1.0-B978-0-7234-3541-9..00021-3--s0015. Accessed Jan. 3, 2011.
  3. Reichman R. Clinical presentation and diagnosis of human papillomavirus infections. http://www.uptodate.com/home/index.html. Accessed Jan. 3, 2011.
  4. Genital HPV infection: Fact sheet. Centers for Disease Control and Prevention. http://www.cdc.gov/std/HPV/STDFact-HPV.htm. Accessed Jan. 3, 2011.
  5. Molpus KL, et al. Gynecologic cancers. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4160-2805-5..50214-7--cesec29&isbn=978-1-4160-2805-5&sid=1101118090&type=bookPage§ionEid=4-u1.0-B978-1-4160-2805-5..50214-7--cesec40&uniqId=230973572-4#4-u1.0-B978-1-4160-2805-5..50214-7--cesec40. Accessed Jan. 4, 2011.
  6. Goldstein BG, et al. Cutaneous warts. http://uptodate.com.home/index.html. Accessed Jan. 4, 2011.
  7. Warts. American Academy of Dermatology. http://aad.org/publications/pamphlets/common_warts.html. Accessed Jan. 4, 2011.
  8. Breen E, et al. Condylomata acuminata (anogenital warts). http://uptodate.com/home/index.html. Accessed Jan. 4, 2011.
  9. Human papillomaviruses and cancer. National Cancer Institute. http://www.cancer.gov/cancertopics/factsheet/Risk/HPV. Accessed Jan. 4, 2011.
  10. Centers for Disease Control and Prevention, et al. Recommendations on the use of quadrivalent human papillomavirus vaccine in males — Advisory Committee on Immunization Practices (ACIP). MMWR Recommendations and Reports. 2011:60;1705.
DS00906 Jan. 20, 2012

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