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Risks

By Mayo Clinic staff

As with any screening test, an HPV test carries the risk of false-positive or false-negative results.

  • False-positive. A false-positive test result indicates that you have a high-risk type of HPV when you really don't. A false-positive result could lead to an unnecessary follow-up procedure, such as colposcopy or biopsy, and undue anxiety over the test results.
  • False-negative. A false-negative test result means you really do have an HPV infection, but the test indicates that you don't. This might cause a delay in appropriate follow-up tests or procedures.
References
  1. Making sense of your Pap and HPV test results. Centers for Disease Control and Prevention. http://www.cdc.gov/std/hpv/pap/default.htm. Accessed Jan. 17, 2012.
  2. Thinking about testing for HPV? American Cancer Society. http://www.cancer.org/docroot/CRI/content/CRI_2_6x_Thinking_About_Testing_for_HPV.asp?sitearea=&level=. Accessed Jan. 17, 2012.
  3. Human papillomavirus: HPV information for clinicians. Centers for Disease Control and Prevention. http://www.cdc.gov/std/hpv/common-clinicians/ClinicianBro-fp.pdf. Accessed Jan. 17, 2012.
  4. Sirovich BE, et al. Screening for cervical cancer. http://www.uptodate.com/home/index.html. Accessed Jan. 17, 2012.
  5. Solomon D, et al. Statement on HPV DNA test utilization. Journal of Lower Genital Tract Disease. 2009;13:135.
  6. Bosch FX. Human papillomavirus: Science and technologies for the elimination of cervical cancer. Expert Opinion Pharmacotherapy. 2011;12:2189.
MY01110 May 15, 2012

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