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Risk factors

By Mayo Clinic staff

In many cases, the exact event leading to hydrocephalus is unknown. However, a number of developmental or medical problems can contribute to or trigger hydrocephalus.

Newborns
Hydrocephalus present at birth (congenital) or shortly after birth may occur because of any of the following:

  • Abnormal development of the central nervous system that can obstruct the flow of cerebral spinal fluid
  • Bleeding within the ventricles, a possible complication of premature birth
  • Infection in the uterus during a pregnancy, such as rubella or syphilis, that can cause inflammation in fetal brain tissues

Other contributing factors
Other factors that can contribute to hydrocephalus among any age group include:

  • Lesions or tumors of the brain or spinal cord
  • Central nervous system infections, such as bacterial meningitis or mumps
  • Bleeding in the brain from stroke or head injury
  • Other traumatic injury to the brain
References
  1. Hydrocephalus. American Association of Neurological Surgeons. http://www.aans.org/Patient%20Information/Conditions%20and%20Treatments/Hydrocephalus.aspx. Accessed June 11, 2011.
  2. Hydrocephalus fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/hydrocephalus/detail_hydrocephalus.htm. Accessed June 10, 2011.
  3. Fishman MA. Hydrocephalus. http://www.uptodate.com/home/index.html. Accessed May 10, 2011.
  4. Diagnosis of hydrocephalus. Hydrocephalus Association. https://www.hydroassoc.org/hydrocephalus-education-and-support/learning-about-hydrcephalus/diagnosis-of-hydrocephalus. Accessed June 11, 2011.
  5. Graff-Radford NR. Normal pressure hydrocephalus. http://www.uptodate.com/home/index.html. Accessed June 10, 2011.
  6. Life-threatening complications of hydrocephalus. Hydrocephalus Association. https://www.hydroassoc.org/hydrocephalus-education-and-support/learning-about-hydrcephalus/life-threatening-complications-of-hydrocephalus. Accessed June 11, 2011.
  7. Hamilton MG. Treatment of hydrocephalus in adults. Seminars in Pediatric Neurology. 2009;16:34.
  8. Meningococcal vaccine: Who and when to vaccinate. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/vpd-vac/mening/who-vaccinate.htm. Accessed June 28, 2011.
  9. Wetjen NM (expert opinion). Mayo Clinic, Rochester, Minn. July 6, 2011.
DS00393 Sept. 13, 2011

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