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Symptoms

By Mayo Clinic staff

Hyperparathyroidism is often diagnosed before signs or symptoms of the disorder are apparent. When symptoms do occur, they are the result of damage or dysfunction in other organs or tissues due to high calcium levels circulating in the blood or too little calcium in bones.

Symptoms may be so mild and nonspecific that they don't seem at all related to parathyroid function, or they may be severe. The range of signs and symptoms include:

  • Fragile bones that easily fracture (osteoporosis)
  • Kidney stones
  • Excessive urination
  • Abdominal pain
  • Tiring easily or weakness
  • Depression or forgetfulness
  • Bone and joint pain
  • Frequent complaints of illness with no apparent cause
  • Nausea, vomiting or loss of appetite

When to see a doctor
See your doctor if you have any signs or symptoms of hyperparathyroidism. These symptoms could be caused by any number of disorders, including some with serious complications. It's important to get a prompt, accurate diagnosis and appropriate treatment.

References
  1. Hyperparathyroidism. National Institute of Diabetes and Digestive and Kidney Diseases. http://www.endocrine.niddk.nih.gov/pubs/hyper/hyper.htm. Accessed March 3, 2011.
  2. El-Hajj Fuleihan G. Diagnosis and differential diagnosis of primary hyperparathyroidism. http://www.uptodate.com/home/index.html. Accessed March 1, 2011.
  3. El-Hajj Fuleihan G. Clinical manifestations of primary hyperparathyroidism. http://www.uptodate.com/home/index.html. Accessed March 1, 2011.
  4. Potts JT. Diseases of the parathyroid gland and other hyper- and hypocalcemic disorders. In: Fauci AS, et al. Harrison's Online. 17th ed. New York, N.Y.: The McGraw-Hill Companies; 2008. http://www.accessmedicine.com/content.aspx?aID=2903222&searchStr=hyperparathyroidism#2903222. Accessed Feb. 28, 2011.
  5. El-Hajj Fuleihan G. Pathogenesis and etiology of primary hyperthyroidism. http://www.uptodate.com/home/index.html. Accessed March 1, 2011.
  6. Fitzgerald PA. Hyperparathyroidism. In: McPhee SJ, et al. Current Medical Diagnosis and Treatment. 50th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/content.aspx?aID=14894&searchStr=hyperparathyroidism. Accessed March 1, 2011.
  7. Silverstein SJ. Management of primary hyperthyroidism. http://www.uptodate.com/home/index.html. Accessed March 1, 2011.
  8. Estrogen and progestin combination (Ovarian hormone therapy) (Oral route). Micromedex Healthcare Series. http://www.micromedex.com. Accessed March 3, 2011.
  9. Bisphosphonates. Micromedex Healthcare Series. http://www.micromedex.com. Accessed March 3, 2011.
  10. Dietary supplement fact sheet: Vitamin D. Office of Dietary Supplements. http://ods.od.nih.gov/factsheets/VitaminD-QuickFacts. Accessed March 3, 2011.
  11. Dietary supplement fact sheet: Calcium. Office of Dietary Supplements. http://ods.od.nih.gov/factsheets/Calcium-QuickFacts. Accessed March 3, 2011.
DS00396 May 13, 2011

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