Definition
By Mayo Clinic staffHyperthyroidism (overactive thyroid) is a condition in which your thyroid gland produces too much of the hormone thyroxine. Hyperthyroidism can accelerate your body's metabolism significantly, causing sudden weight loss, a rapid or irregular heartbeat, sweating, and nervousness or irritability.
Several treatment options are available if you have hyperthyroidism. Doctors use anti-thyroid medications and radioactive iodine to slow the production of thyroid hormones. Sometimes, treatment of hyperthyroidism involves surgery to remove all or part of your thyroid gland. Although hyperthyroidism can be serious if you ignore it, most people respond well once hyperthyroidism is diagnosed and treated.
- Hyperthyroidism. The American Thyroid Association. http://www.thyroid.org/what-is-hyperthyroidism. Accessed July 17, 2012.
- Soetters MR, et al. Optimal management of Graves orbitopathy: A multidisciplinary approach. The Netherlands Journal of Medicine. 2011;69:302.
- Brandt F, et al. A critical review and meta-analysis of the association between overt hyperthyroidism and mortality. European Journal of Endocrinology. 2011;165:491.
- Graves' disease. Womenshealth.gov. http://www.womenshealth.gov/faq/graves-disease.cfm. Accessed July 17, 2012.
- Hyperthyroidism. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/sec12/ch152/ch152e.html. Accessed July 25, 2012.
- Graves' disease. National Endocrine and Metabolic Diseases Information Service. http://www.endocrine.niddk.nih.gov/pubs/graves/Graves.pdf. Accessed July 25, 2012.
- Hyperthyroidism. National Endocrine and Metabolic Diseases Information Service. http://www.endocrine.niddk.nih.gov/pubs/hyperthyroidism/index.aspx. Accessed July 25, 2012.
- Dietary Reference Intakes for calcium and vitamin D. Institute of Medicine. http://www.iom.edu/vitamind. Accessed July 17, 2012.
- Bahn RS, et al. Hyperthyroidism and other causes of thyrotoxicosis: Management guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists. Thyroid. 2011;21:593.
- Thyroid problems. Hormone Health Network. http://www.hormone.org/thyroid_problems.cfm. Accessed July 26, 2012.
- Stan MN, et al. The evaluation and treatment of Graves ophthalmopathy. Medical Clinics of North America. 2012;96:311.
- Schwartz KM, et al. Dermopathy of Grave's disease (pretibial myxedema): Long-term outcome. The Journal of Clinical Endocrinology & Metabolism. 2002;77:438.
- Nippoldt TB (expert opinon). Mayo Clinic, Rochester, Minn. Aug. 14, 2012.


Find Mayo Clinic on