Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get StartedDefinition
By Mayo Clinic staffHypertrophic cardiomyopathy (HCM) is a disease in which the heart muscle (myocardium) becomes abnormally thick — or hypertrophied. This thickened heart muscle can make it harder for the heart to pump blood. Hypertrophic cardiomyopathy may also affect the heart's electrical system.
Hypertrophic cardiomyopathy often goes undiagnosed because many of those with hypertrophic cardiomyopathy have few, if any, symptoms. In a small number of people with this condition, the thickened heart muscle can cause signs and symptoms, such as shortness of breath and problems in the heart's electrical system resulting in life-threatening abnormal heart rhythms (arrhythmias).
Fortunately, most people with hypertrophic cardiomyopathy lead normal lives with no significant problems.
- Cardiomyopathy. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4468. Accessed Jan. 20, 2009.
- Maron BJ. Hypertrophic cardiomyopathy. In: Libby P, et al, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/117866989-4/796148825/1549/451.html#4-u1.0-B978-1-4160-4106-1..50068-6_7427. Accessed Jan. 20, 2009.
- Elliot P, et al. Clinical manifestations of hypertrophic cardiomyopathy. http://www.uptodate.com/home/index.html. Accessed Jan. 20, 2009.
- Hypertrophic cardiomyopathy. The Merck Manuals Online Medical Library: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec07/ch084666/ch084666c.html. Accessed Jan. 20, 2009.
- Ferri F. Cardiomyopathy, hypertrophic. In: Ferri FF. Ferri's Clinical Advisor 2009. St. Louis, Mo.: Mosby; 2008:162.
- You JJ, et al. Life expectancy gains and cost-effectiveness of implantable cardioverter/defibrillators for the primary prevention of sudden cardiac death in patients with hypertrophic cardiomyopathy. American Heart Journal. 2007;154:899.
- Pigozzi F, et al. Sudden death in competitive athletes. Clinics in Sports Medicine. 2008;27:153.
- Maron BJ. Hypertrophic dardiomyopathy and other causes of sudden cardiac death in young competitive athletes, with considerations for preparticipation screening and criteria for disqualification. Cardiology Clinics. 2007;25:399.
- Ingles J. Psychosocial impact of specialized cardiac genetic clinics for hypertrophic cardiomyopathy. Genetics in Medicine. 2008;10:117.
- Morgan JF, et al. Psychiatric disorders in hypertrophic cardiomyopathy. General Hospital Psychiatry. 2008;30:49.