DefinitionBy Mayo Clinic staff
Hypopituitarism is a rare disorder in which your pituitary gland either fails to produce one or more of its hormones or doesn't produce enough of them.
The pituitary is a small bean-shaped gland situated at the base of your brain, behind your nose and between your ears. Despite its size, this gland secretes hormones that influence nearly every part of your body.
In hypopituitarism, you have a short supply of one or more of these pituitary hormones. This deficiency can affect any number of your body's routine functions, such as growth, blood pressure and reproduction.
You'll likely need medications for the rest of your life to treat hypopituitarism, but your symptoms can be controlled.
- Generalized hypopituitarism. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec12/ch151/ch151c.html. Accessed Feb. 22, 2013.
- Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Feb. 22, 2013.
- Papadakis MA, et al. Current Medical Diagnosis & Treatment 2013. 52nd ed. New York, N.Y.: The McGraw-Hill Companies; 2013. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=1. Accessed Feb. 22, 2013.
- Appelman-Dijkstra NM, et al. Pituitary dysfunction in adult patients after cranial radiotherapy: Systematic review and meta-analysis. Journal of Clinical Endocrinology & Metabolism. 2011;96:2330.
- Toogood AA, et al. Hypopituitarism: Clinical features, diagnosis and management. Endocrinology and Metabolism Clinics of North America. 2008;37:235.