Hypoplastic left heart syndrome

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Complications

By Mayo Clinic staff

Without surgery, hypoplastic left heart syndrome is fatal, usually within the first week or two of life.

With treatment, many babies survive, although most will have complications later in life. Some of the complications include:

  • Tiring easily when participating in sports or other exercise
  • Heart rhythm abnormalities (arrhythmias)
  • Fluid buildup in the lungs, abdomen, legs and feet (edema)
  • Formation of blood clots that may lead to a pulmonary embolism or stroke
  • Developmental problems related to the brain and nervous system
  • Need for additional heart surgery or transplantation
References
  1. Marshall A. Hypoplastic left heart syndrome. http://www.uptodate.com/index. Accessed June 27, 2012.
  2. Facts about hypoplastic left heart syndrome. Centers for Disease Control and Prevention. http://www.cdc.gov/ncbddd/heartdefects/HLHS.html. Accessed July 24, 2012.
  3. Brenner JI, et al. Hypoplastic left heart syndrome and other left heart disease: Evolution of understanding from population-based analysis to molecular biology and back again — A brief overview. Cardiology in the Young. 2011;21:23.
  4. Grossfield P, et al. Hypoplastic left heart syndrome: New genetic insights. Journal of the American College of Cardiology. 2009;53:1072.
  5. Murtuza B, et al. Changing attitudes to the management of hypoplastic left heart syndrome: A European perspective. Cardiology in the Young. 2011;21:148.
  6. Said SM, et al. Longer-term issues for young adults with hypoplastic left heart syndrome: Contraception, pregnancy, transition, transfer, counselling, and re-operation. Cardiology in the Young. 2011;21: 93.
  7. Goldberg CS, et al. Neurodevelopment and quality of life for children with hypoplastic left heart syndrome: Current knowns and unknowns. Cardiology in the Young. 2011;21: 88.
  8. Waltzman M. Initial evaluation of shock in children. http://www.uptodate.com/index. Accessed June 27, 2012.
DS00744 Aug. 24, 2012

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