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Causes
By Mayo Clinic staffHypospadias is present at birth (congenital). The exact reason this defect occurs is unknown. Sometimes hypospadias is inherited.
As the penis develops in a male fetus, certain hormones stimulate the formation of the urethra and foreskin. Hypospadias results when a malfunction occurs in the action of these hormones, causing the urethra to develop abnormally.
- Kraft KH, et al. Hypospadias. Urologic Clinics of North America 2010;37:167.
- Hypospadias. American Urology Association. www.urologyhealth.org/print/index.cfm?topic=96. Accessed Dec. 3, 2010.
- Yiee JH. Environmental factors in genitourinary development. Journal of Urology. 2010;174:34.
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