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Question

Hypothyroidism and infertility: Any connection?

For women, is there any connection between hypothyroidism and infertility?

Answer

from Mary M. Gallenberg, M.D.

Underactive thyroid (hypothyroidism) is a condition in which the thyroid gland doesn't produce enough of certain important hormones. For women, there's sometimes a link between hypothyroidism and infertility. Low levels of thyroid hormone can interfere with ovulation, which impairs fertility. In addition, some of the underlying causes of hypothyroidism — such as certain autoimmune or pituitary disorders — impair fertility.

For women, treating hypothyroidism is an important part of any effort to correct infertility. However, sometimes it's not possible to fully restore fertility. In these cases, other interventions may be needed to treat infertility.

If you have hypothyroidism and hope to become pregnant, work with your doctor to make sure your hypothyroidism is under control. Seek additional help from an infertility specialist if needed.

If you have hypothyroidism and become pregnant, tell your doctor promptly. Close monitoring of your thyroid hormone level during pregnancy can promote normal fetal development and reduce the risk of miscarriage.

Next question
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References
  1. Surks MI. Clinical manifestations of hypothyroidism. http://www.uptodate.com/home/index.html. Accessed Aug. 3, 2010.
  2. Brassard M, et al. Basic infertility including polycystic ovary syndrome. The Medical Clinics of North America. 2008;92:1163.
  3. Mestman JH. Thyroid and parathyroid diseases in pregnancy. In: Gabbe SG, et al. Obstetrics: Normal and Problem Pregnancies. 5th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2007. http://www.mdconsult.com/das/book/body/212819723-10/0/1528/403.html?tocnode=57027959&fromURL=403.html#4-u1.0-B978-0-443-06930-7..50040-2_1720. Accessed Aug. 3, 2010.
AN01436 Sept. 21, 2010

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